Virtual Reality for Neuropathic Pain in Spinal Cord Injury

This study is looking into whether playing virtual reality (VR) walking games can help reduce neuropathic pain (nerve pain, often described as sharp, burning, or electric) in adults with chronic spinal cord injury (SCI). You would wear a special headset to see virtual legs and arms in a virtual world. The study aims to see if this VR experience, by creating the "illusion" of walking, can help correct a mismatch between what your brain expects and what your body is doing, which scientists believe contributes to neuropathic pain. The main goal is to measure changes in your pain intensity over up to 18 months. This study is currently recruiting 250 participants and is open to individuals aged 18 and older with complete SCI (ASIA A classification) who experience daily neuropathic pain of at least 4 out of 10 for three or more months.

Study design
This interventional study plans to enroll 250 participants. It compares two different virtual reality walking games.
What's involved
Your pain intensity will be measured at the beginning of the study and then regularly until the final follow-up, which can be up to 18 months later.
Compensation
Not stated in the trial record.
Follow-up
Participants will be followed for changes in pain intensity for up to 18 months after starting the study.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT05005026

Virtual Walking Intervention for Neuropathic Pain in Spinal Cord Injury

Recruiting
NAAges 18+InterventionalTreatment
Texas A&M University
~250 participants
Updated 2025-12-17 on ClinicalTrials.gov
What's tested:VR Game 1VR Game 2

At a glance

Recruiting sites
2 of 3 listed sites are recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Change in Pain Intensity
Measured over Baseline - final follow up (up to 18 months)
Spinal Cord Injuries
Neuropathic Pain
3 sites across 3 states
Alabama1
Texas1
New South Wales1
  • Zina Trost, PhD · PRINCIPAL_INVESTIGATOR · Texas A&M University

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  • Change in Pain IntensityBaseline - final follow up (up to 18 months)

    The Numeric Rating Scale (NRS) measures pain intensity via 0-10 numeric rating scale 0-10 where 0 is no pain and 10 is the worst pain imaginable.