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Geriatric Evaluation and Management With Survivorship Health Education (GEM-S) for Older Cancer Survivors

This study, called GEM-S, is for older adults who have survived cancer, specifically lymphoma or solid tumors. It compares a special program that includes a comprehensive geriatric assessment (a full health check-up for older adults) and health education sessions with the usual follow-up care. The goal is to see if GEM-S can improve your physical ability to do daily activities, your mental well-being, and your memory after cancer treatment. Researchers will measure your physical function up to 6 months after starting the program. This study is looking for 668 participants and is currently unclear about its recruitment status. The study aims to understand if GEM-S helps improve physical, mental, and memory functions in older cancer survivors.

Study design
This interventional study plans to enroll 668 participants. It compares a special program (GEM-S) to usual follow-up care.
What's involved
You would either receive usual follow-up care or participate in a comprehensive geriatric assessment, health education sessions, and an exercise program. There will also be questionnaires for ancillary studies.
Compensation
Not stated in the trial record.
Follow-up
Your physical function will be measured up to 6 months after starting the program.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT05006482

Geriatric Evaluation and Management With Survivorship Health Education for Older Survivors of Cancer, GEM-S Trial

Recruiting
PHASE3Ages 18+InterventionalSupportive care
University of Rochester
~668 participants
Updated 2026-01-13 on ClinicalTrials.gov
What's tested:Best PracticeComprehensive Geriatric AssessmentEducational InterventionExercise InterventionQuestionnaire AdministrationTailored Intervention

At a glance

Recruiting sites
44 of 45 listed sites are recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Patient-reported physical function
Measured over Up to 6 months

Conditions

Lymphoma
Malignant Solid Neoplasm

Explore related trials

LymphomaSolid Neoplasm

NCT05006482

Where you'd take part

This study runs at 45 sites. They're the same protocol — you choose where, and that choice sets who your contact draft is addressed to.

  • Chesapeake Regional Medical Center

    Chesapeake, Virginiastudy coordinator listed

    Recruiting

  • Community Medical Center

    Scranton, Pennsylvaniastudy coordinator listed

    Recruiting

  • Fairview Southdale Hospital

    Edina, Minnesotastudy coordinator listed

    Recruiting

  • Geisinger Cancer Center Dickson City

    Dickson City, Pennsylvaniastudy coordinator listed

    Recruiting

  • Geisinger Medical Center

    Danville, Pennsylvaniastudy coordinator listed

    Recruiting

  • Geisinger Wyoming Valley/Henry Cancer Center

    Wilkes-Barre, Pennsylvaniastudy coordinator listed

    Recruiting

  • Hawaii Cancer Care - Westridge

    ‘Aiea, Hawaiistudy coordinator listed

    Recruiting

  • Hawaii Cancer Care Inc - Waterfront Plaza

    Honolulu, Hawaiistudy coordinator listed

    Recruiting

Sites open and close at different times, so the status above is per site — it can differ from the study's overall status.

Study leadership

  • Supriya G Mohile · PRINCIPAL_INVESTIGATOR · University of Rochester NCORP Research Base

Who to contact

Site Public Contact
800-338-2948
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Eligibility criteria

Inclusion

PRACTICE CRITERIA: Participating practice clusters will be required to identify one (or more) oncologist and/or advanced practice practitioner (APPs; i.e., nurse practitioners, or physician assistants) as part of study eligibility. If another clinician is interested in participating, please contact University of Rochester Cancer Center (URCC) National Cancer Institute Community Oncology Research Program (NCORP) Research Base (RB) for approval
Oncologists/APPs/other clinicians must be licensed to practice
Oncologists/APPs/other clinicians must not have a plan to leave or retire from the NCORP practice within one year of enrolling into the study
PRACTICE CRITERIA: Support/buy-in from oncology physicians and/or APPs and/or other clinicians who are willing to participate in training and study procedures and enroll cancer survivors
ENTRY CRITERIA FOR ONCOLOGY PHYSICIANS/APPS/OTHER CLINICIANS: Oncology physicians/APPs/other clinicians must work at a participating site with no plans to leave that practice or retire within one year of enrollment into the study. We do not require that any or all oncology physicians and/or APPs at a practice setting agree to participate. Only one clinician is required for the practice cluster to be eligible. If another clinician (other than oncology physician or APP) is interested in participating, please contact URCC NCORP RB for approval
CANCER SURVIVORS: 65 years or older
CANCER SURVIVORS: Have completed or will have completed curative-intent treatment (e.g., surgery, chemotherapy, chemotherapy with radiation) for any solid tumor or lymphoma malignancy in last 6 months. If the survivor is receiving curative-intent chemotherapy, run-in study procedures can occur during the last 6 weeks of chemotherapy.
Cancer survivors who will receive or are receiving other treatments (e.g., hormonal treatment, monoclonal antibodies, immunotherapy, radiation) are eligible
For patients receiving neoadjuvant chemotherapy for curative intent, the run-in and baseline procedures can occur before or after surgery. Patients should be enrolled within 6 months from the end of surgery
CANCER SURVIVORS: Be willing and able to come in for study visits or willing to undergo informed consent and assessments remotely via tele-health visits
CANCER SURVIVORS: Be willing and able to provide informed consent and must sign consent in-person or remotely if it is not convenient or feasible to provide informed consent in-person
CANCER SURVIVORS: Speak and understand English and/or Spanish. Spanish-speaking cancer survivors are eligible as long as there are appropriate resources in place for completion of study procedures at the practice site. Registration for Spanish-speaking cancer survivors must be approved by the URCC NCORP Research Base after a phone call to determine the feasibility for the practice to enroll a Spanish-speaking participant
CAREGIVERS: 18 years or older
CAREGIVERS: Selected by the cancer survivor when asked if there is a "family member, partner, friend or caregiver (age 18 years or older) with whom you discuss or who can be helpful in health-related matters." A caregiver need not be someone who lives with the cancer survivor or provides direct hands-on care
CAREGIVERS: Speak and understand English and/or Spanish. Spanish-speaking caregivers are eligible as long as there are appropriate resources in place for completion of study procedures. Registration for Spanish-speaking caregivers must be approved by the URCC NCORP Research Base after a phone call to determine the feasibility for the practice to enroll a Spanish-speaking participant

Exclusion

CANCER SURVIVORS: Have a condition that precludes their ability to participate in informed consent or procedures (e.g., dementia)
CAREGIVERS: Caregivers unable to understand the informed consent form or study procedures due to cognitive, health, or sensory impairment will be excluded
Capacity to conduct informed consent procedures and study procedures will be determined by the coordinators in collaboration with the cancer survivors' oncologists. These procedures are similar to that of URCC 13070, which enrolled caregivers of older patients with advanced cancer

What this trial measures

  • Patient-reported physical functionUp to 6 months

    Will be assessed by the Functional Assessment of Cancer Therapy Physical Well-Being (FACIT-PWB) Subscale in older cancer survivors. The FACIT-PWB is 7-items as part of a larger 40-item FACIT-F questionnaire. Each question uses a 5-point rating scale (0 = Not at all; 1 = A little bit; 2 = Somewhat; 3 = Quite a bit; and 4 = Very much).