Understanding Kidney Health in Youth with Diabetes and Obesity (PANTHER Study)
This observational study, called the PANTHER Study, is looking at how puberty affects kidney health in young people (ages 8-14) who have type 2 diabetes, pre-diabetes, or obesity. Researchers want to understand why kidney disease often starts early in life for these young people. You might be able to join if you have certain levels of HbA1c (a measure of blood sugar) or BMI (Body Mass Index), and do not have type 1 diabetes or existing kidney disease. The study uses diagnostic agents like Aminohippurate Sodium Inj 20%, Iohexol Inj 300 MG/ML, and Dextran 40 to measure how well your kidneys are working, specifically your effective renal plasma flow (ERPF) and glomerular filtration rate (GFR) over 3 hours. The study aims to enroll 100 participants.
- Study design
- This is an observational study, meaning researchers will observe participants without assigning specific treatments. It plans to enroll 100 participants.
- What's involved
- Not specified in the trial record.
- Compensation
- Not stated in the trial record.
- Follow-up
- The primary measurements for kidney function (ERPF and GFR) are taken at 3 hours.
AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.
Puberty, Diabetes, and the Kidneys, When Eustress Becomes Distress (PANTHER Study)
At a glance
Conditions
Where it's being run
2 sites across 2 statesStudy leadership
- Petter Bjornstad, MD · PRINCIPAL_INVESTIGATOR · University of Washington - Medicine Diabetes Institute
Who to contact
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Do you actually qualify for this trial?
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Inclusion
Exclusion
What this trial measures
- Effective renal plasma flow (ERPF)3 Hours
Measured by PAH Clearance
- Glomerular Filtration Rate (GFR)3 hours
Measured by iohexol clearance