Heart Health in Locally Advanced Lung Cancer Patients Receiving Chemoradiation
This study is for people with non-small cell lung cancer that has spread to nearby tissue or lymph nodes (locally advanced). It aims to understand how chemoradiation treatment affects your heart and overall heart fitness. Researchers will use tests like the 6 Minute Walk Functional Test, echocardiograms (ultrasound of the heart), and stress tests to see if your heart health changes. They also want to see if personalizing your cancer treatment based on your individual risk can help protect your heart. The study will look for an increase in a heart injury marker (hs-TnT) and serious heart problems within 12 months of finishing treatment. This study plans to enroll 100 participants.
- Study design
- This is an interventional study, meaning you will receive specific tests and procedures. It plans to enroll 100 participants.
- What's involved
- You will undergo various tests including a 6 Minute Walk Functional Test, blood and urine collection, CT scans, echocardiograms, and stress tests at different times before, during, and after your chemoradiation treatment. This will occur over a period of up to 24 months for some tests.
- Compensation
- Not stated in the trial record.
- Follow-up
- After completing study treatment, you will be followed annually for up to 10 years.
AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.
Cardiovascular Injury and Cardiac Fitness in Locally Advanced Non-Small Cell Lung Cancer Patients Receiving Model Based Personalized Chemoradiation
At a glance
Conditions
Where it's being run
1 sites across 1 statesStudy leadership
- Zhongxing Liao, MD · PRINCIPAL_INVESTIGATOR · M.D. Anderson Cancer Center
Who to contact
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What this trial measures
- Increase in level of hs-TnT >= 5ng/Lup to 24 months
Baseline up to end or chemoradiation (CRT)
- Incidence of grade >= 2 cardiovascular eventsWithin 12-month of completion of CRT]
Defined by Common Terminology Criteria for Adverse Events version 5.0.