Rhythmic Light Therapy for Mild Cognitive Impairment and Alzheimer's Disease
This study is testing different types of light therapy for people with mild cognitive impairment or mild Alzheimer's disease. Researchers want to see if specific light treatments can improve thinking and memory. You would be randomly assigned to one of four groups: a Rhythmic Light (40 hertz flicker) or a Placebo Rhythmic Light (random flicker), each delivered with either Circadian-Effective Light (narrowband blue light) or Placebo Light (narrowband red light). To join, you need to be diagnosed with mild cognitive impairment or mild Alzheimer's, have sleep problems, and live at home or in an assisted living facility. The main goal is to see how these light therapies affect your cognition, measured by the Montreal Cognitive Assessment (MoCA) at different times during the study. This study is currently recruiting 120 participants.
- Study design
- This is an interventional study with 120 planned participants. You would be randomly placed into one of four groups, each receiving a different light therapy.
- What's involved
- After a baseline week, you would use your assigned light therapy for two hours in the morning for 8 weeks. There will be assessments at the start, after 9 weeks, and after 14 weeks.
- Compensation
- Not stated in the trial record.
- Follow-up
- Your cognition will be assessed at the end of week 9 and again at the end of week 14, after a 4-week break from the light therapy.
AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.
Phase 2 - Rhythmic Light Therapy for Alzheimer's Disease Patients
At a glance
Conditions
Where it's being run
2 sites across 1 statesStudy leadership
- Mariana Figueiro, PhD · PRINCIPAL_INVESTIGATOR · Icahn School of Medicine at Mount Sinai
Who to contact
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Do you actually qualify for this trial?
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Inclusion
Exclusion
What this trial measures
- Cognition using the Montreal Cognitive Assessment (MoCA)baseline
The Montreal Cognitive Assessment is a one-page, 30-point test that can be administered in 10 minutes. It assesses short-term memory, visuospatial abilities, executive functions, attention, concentration and working memory, language, and orientation to time and place. total score ranging from 0 to 30 units on a scale, with higher score indicating better cognitive global function.
- Cognition using the Montreal Cognitive Assessment (MoCA)at the end of week 9
The Montreal Cognitive Assessment is a one-page, 30-point test that can be administered in 10 minutes. It assesses short-term memory, visuospatial abilities, executive functions, attention, concentration and working memory, language, and orientation to time and place. total score ranging from 0 to 30 units on a scale, with higher score indicating better cognitive global function.
- Cognition using the Montreal Cognitive Assessment (MoCA)at the end of week 14
The Montreal Cognitive Assessment is a one-page, 30-point test that can be administered in 10 minutes. It assesses short-term memory, visuospatial abilities, executive functions, attention, concentration and working memory, language, and orientation to time and place. total score ranging from 0 to 30 units on a scale, with higher score indicating better cognitive global function.