Comparing Bleeding Prevention in Hemophilia A During Sports

This study is looking at how well two different treatments, Emicizumab and Factor VIII (FVIII), prevent bleeding in young people with moderate to severe Hemophilia A (a genetic bleeding disorder where your blood doesn't clot properly) who play sports. Researchers want to see which treatment leads to fewer bleeding episodes over two years. You might be able to join if you are between 6 and 19 years old, have moderate to severe Hemophilia A without inhibitors (antibodies that can make FVIII treatment less effective), and are already on one of these standard treatments. This is an observational study, meaning researchers will watch and collect information about your current treatment and how it affects bleeding.

Study design
This is an observational study planning to include 72 participants. It compares two groups: those on standard Emicizumab prophylaxis and those on standard FVIII prophylaxis.
What's involved
Not specified in the trial record.
Compensation
Not stated in the trial record.
Follow-up
Participants will be followed for two years to measure the number of bleeding events.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT05022459

Prevention of Bleeding in Patients With Moderate and Severe Hemophilia A Playing Sports: A Comparison Between Factor VIII and Emicizumab Prophylaxis

Recruiting
Not specifiedAges 6–19Observational
Wayne State University
~72 participants
Updated 2026-07-02 on ClinicalTrials.gov
What's tested:EmicizumabFVIII

At a glance

Recruiting sites
10 of 10 listed sites are recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Number of bleeds
Measured over 2 years
Hemophilia A
10 sites across 9 states
California2
Arkansas1
Florida1
Illinois1
Indiana1
Massachusetts1
Michigan1
Ohio1
  • Meera Chitlur, MD · PRINCIPAL_INVESTIGATOR · Wayne State University

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  • Number of bleeds2 years

    Number of bleeds without trauma, during participation in sports activities