Brain Stimulation for Hand Strength in Brain Tumor Patients

This study is looking at how different ways of using brain stimulation during surgery might affect hand strength and movement in people with brain tumors. The intervention being tested is called "Intraoperative Brain Stimulation - Alternate Stimulation Parameters." Researchers want to find out which stimulation settings (parameters) during awake brain surgery (craniotomy) can either stop or help hand movement. You might be able to join if you are between 18 and 75 years old, have a brain tumor that affects the part of the brain controlling hand movement in the non-dominant hemisphere, and have good overall health. The study aims to enroll 20 participants, but its current recruitment status is unclear.

Study design
This is an interventional study, meaning participants will receive a specific treatment. It plans to enroll 20 participants.
What's involved
Participants will undergo intraoperative direct electrical stimulation (DES) mapping during awake craniotomy.
Compensation
Not stated in the trial record.
Follow-up
The primary outcome is measured during the operation (Intra-op), so follow-up after treatment is not specified.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT05023434

A Study to Measure the Effect of Brain Stimulation on Hand Strength and Function in Patients With Brain Tumors

Recruiting
NAAges 18–75InterventionalDevice feasibility
Medical College of Wisconsin
~20 participants
Updated 2026-05-11 on ClinicalTrials.gov
What's tested:Intraoperative Brain Simulation - Alternate Stimulation Parameters

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Identify DES parameters that lead to either interruption or facilitation of hand movement during awake craniotomies
Measured over Intra-op
Brain Tumor
Brain Cancer
Motor Cortex; Lesion
1 sites across 1 states
Wisconsin1

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  • Identify DES parameters that lead to either interruption or facilitation of hand movement during awake craniotomiesIntra-op

    The categorization of stimulation frequencies (10, 30, 60, 130, and 250 Hz) as either inhibitory, facilitatory, or neutral, based on their impact on the finger individualization score.