This study is looking at how a capsule called Sodium Hyaluronate (HA35) might affect your liver after drinking alcohol. You could be eligible if you are a healthy adult between 21 and 65 years old, drink a moderate amount of alcohol, and don't have certain chronic illnesses. Participants will receive either Sodium Hyaluronate or a placebo (an inactive capsule). Researchers will measure changes in liver enzymes (Aspartate Aminotransferase or AST, and Alanine Aminotransferase or ALT) from the start of the study to day 4 to see if HA35 has an effect. The current status of this study is unclear, and it plans to enroll 24 healthy volunteers.

Study design

This is an interventional study that will enroll 24 healthy participants. You will be randomly assigned to receive either Sodium Hyaluronate or a placebo.

What's involved

You will take a capsule for 3 days, then have a 3-4 hour study visit on day 4 involving a medical exam, blood tests, questionnaires, body measurements, urine and stool collection, a sugar drink, an alcohol challenge, and two muscle biopsies. You will also need a designated driver for day 4 and will return on day 5 to drop off a 24-hour urine collection.

Compensation

Not stated in the trial record.

Follow-up

Your liver enzymes (AST and ALT) will be measured from baseline to day 4.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.