This observational study is looking at how a special type of MRI, called 129-Xenon MRI (129-XeMRI), can help understand lung problems in adults who have had a hematopoietic cell transplant (HCT). Researchers want to see if measurements from the 129-XeMRI, which looks at how air moves, exchanges, and circulates in your lungs, match up with other lung tests like spirometry and CT scans. They are studying people who have a lung condition called bronchiolitis obliterans syndrome (BOS), or early signs of it (BOS 0p), or chronic graft-versus-host disease (cGVHD) without lung issues. The study also includes healthy volunteers. The goal is to see if 129-XeMRI can help predict if BOS will get worse over time.

Study design

This is an observational study with a planned enrollment of 25 participants. It is not a treatment study but rather observes and measures lung function.

What's involved

You would undergo a 129-XeMRI scan. The primary measurements will be taken through study completion, which is an average of 1 year.

Compensation

Not stated in the trial record.

Follow-up

Measurements will be taken through study completion, an average of 1 year. There is also a secondary objective to predict BOS progression 6 months after enrollment.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.