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NCT05041166

A Study of [13C]Pyruvate as an Imaging Agent for Magnetic Resonance Imaging in Healthy Volunteers

Enrolling by Invitation
PHASE1Ages 18–80InterventionalDiagnostic
Memorial Sloan Kettering Cancer Center
~50 participants
Updated 2026-02-20 on ClinicalTrials.gov
What's tested:Hyperpolarized [13C] Pyruvate

At a glance

Recruiting sites
0 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Signal-to-noise ratios
Measured over 1 day

Conditions

Healthy Volunteers

Explore related trials

Healthy Volunteers

NCT05041166

Where you'd take part

This study runs at 1 site. They're the same protocol — you choose where, and that choice sets who your contact draft is addressed to.

  • Memorial Sloan Kettering Cancer Center

    New York, New Yorkno site contact published

Sites open and close at different times, so the status above is per site — it can differ from the study's overall status.

Study leadership

  • Vesselin Miloushev, MD · PRINCIPAL_INVESTIGATOR · Memorial Sloan Kettering Cancer Center

Who to contact

This trial hasn't published a contact. View it on ClinicalTrials.gov

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Eligibility criteria

Inclusion

Age between 18-80
Negative serum or urine pregnancy test for female volunteers of childbearing age and potential (as defined by MSKCC Standards \& Guidelines), from assays obtained \<2 weeks prior to study enrollment. Urine pregnancy tests are only valid for the day of test.

Exclusion

Breast-feeding
History of metabolic (e.g. diabetes) and renal functional disorders.
Refusal or inability to tolerate the scanning procedure (e.g., due to claustrophobia)
Acute major illness (e.g., unstable cardiovascular condition, systemic malignant diseases, etc.).
Standard MRI safety screening will be applied (MRI screening questionnaire); volunteers with MR unsafe devices, or conditional devices where research mode is not allowed, will be excluded.

What this trial measures

  • Signal-to-noise ratios1 day

    will be used to assess image quality, and to compare the different technical setups. The setup providing the highest SNR will be considered optimal.