Wet Heparinized Suction for Abdominal Cancer

This study is looking at ways to get better tissue samples from abdominal (belly area) cancers like those in the pancreas, stomach, esophagus, or liver. Doctors will compare two methods during a procedure called EUS-FNB (endoscopic ultrasound with fine needle biopsy). One method involves flushing the needle with heparin, a "blood thinner," and the other uses a salt water solution. They will also see if using a special microsieve helps. You will be randomly assigned to one of these groups. The main goal is to see which method collects more tissue. This study aims to enroll 42 participants across one location in the United States. You can join if you are at least 18 years old, not pregnant, and have a solid abdominal mass that needs to be biopsied.

Study design
This is an interventional study with 42 participants. You will be randomly assigned, like a coin flip, to receive either heparin or saline with the needle, and to have a microsieve used or not.
What's involved
You will undergo an EUS-FNB procedure where the needle will be prepared with either heparin or saline, and a microsieve may or may not be used. The aggregate specimen length will be measured immediately after the procedure.
Compensation
Not stated in the trial record.
Follow-up
The primary outcome, aggregate specimen length, is measured immediately after the procedure.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT05041335

Wet Heparinized Suction for Abdominal Cancer

Not Yet Recruiting
NAAges 18+InterventionalDiagnostic
H. Lee Moffitt Cancer Center and Research Institute
~42 participants
Updated 2025-04-22 on ClinicalTrials.gov
What's tested:wet heparinzed suctionMicrosieveNo heparin flushNo microsieve

At a glance

Recruiting sites
0 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Aggregate specimen length (ASL)
Measured over immediately after the intervention/procedure/surgery
Cancer of Pancreas
Cancer of Stomach
Cancer of Esophagus
Cancer of Liver
Cancer
1 sites across 1 states
Florida1
  • Shaffer Mok, MD · PRINCIPAL_INVESTIGATOR · Moffitt Cancer Center

Opens a ready-to-send draft in your own email app — review before sending.

Do you actually qualify for this trial?

Add a private profile and we'll compare every criterion below against your situation — and tell you which ones are met, uncertain, or excluding.

Check eligibility for this trial ~2 min · HIPAA-protected · delete anytime
Eligibility criteria

Inclusion

Age ≥ 18 year
Non-pregnant Patients
Patients with the presence of a solid abdominal mass as seen on diagnostic imaging \[ie. ultrasound (US), computer tomography (CT) or magnetic resonance imaging (MRI)\] scheduled to undergo EUS examination OR Patients who underwent a prior EUS-FNA/FNB for solid pancreatic mass and did not receive a conclusive diagnosis
Patients with platelet count \> 50,000
Patients with International Normalized Ratio (INR) \< 1.5

Exclusion

Age \< 18 years
Pregnant Patients
Patients who cannot consent for themselves
Patients with anticoagulants or anti-platelet agents (excluding aspirin) within the last 7-10 days
Patients with cystic abdominal masses
Patients with a platelet count \< 50,000
Patients with an INR \> 1.5
Patients with a heparin or porcine allergy
Patients with prior heparin induced thrombocytopenia (HIT)
Patient's with religious aversion to porcine-containing products
  • Aggregate specimen length (ASL)immediately after the intervention/procedure/surgery

    sum length of all pieces of tissue obtained from EUS-FNB