This study is looking at whether a combination of donepezil (a medication) and cognitive remediation therapy (CRT), which helps improve thinking skills, can reduce heavy drinking in people with Alcohol Use Disorder (AUD). You might receive donepezil plus CRT, donepezil with a placebo (inactive) CRT, a placebo medication with CRT, or both placebo medication and placebo CRT. The study aims to enroll 160 participants between 18 and 80 years old who have AUD and can read English. The main goal is to see if these treatments reduce heavy drinking days after 13 weeks. The current status of this study is unclear.

Study design

This is a double-blind, placebo-controlled study, meaning neither you nor your doctors will know which treatment you are receiving. It plans to enroll 160 participants.

What's involved

You would take oral donepezil or a placebo medication daily for 13 weeks. The dose of donepezil would increase after 4 weeks.

Compensation

Not stated in the trial record.

Follow-up

The primary outcome of heavy drinking days is measured at 13 weeks of active intervention.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.