Early Tranexamic Acid (TXA) for Hip Fractures

This study is testing if giving tranexamic acid (TXA), a medicine that helps reduce bleeding, earlier to adults with hip fractures can decrease blood loss and the need for blood transfusions after surgery. You might be able to join if you are an adult (18 or older) with an acute hip fracture needing surgery. The study aims to see if giving TXA in the emergency department, in addition to during surgery, is better than only giving it during surgery. Researchers will measure how much blood you lose and if you need a blood transfusion up to two weeks after your operation. The current recruitment status is unclear.

Study design
This is an interventional study planning to enroll 170 participants, comparing different timings for giving tranexamic acid (TXA).
What's involved
Not specified in the trial record.
Compensation
Not stated in the trial record.
Follow-up
Researchers will follow participants for up to two weeks after surgery to measure blood loss and transfusions.

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NCT05047133

Effect of Early Administration of TXA in Adult Hip Fractures

Recruiting
PHASE2Ages 18+InterventionalPrevention
Ascension Health
~170 participants
Updated 2021-09-16 on ClinicalTrials.gov
What's tested:Tranexamic acid

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Postoperative Blood Transfusion
Measured over Up to two weeks
+1 more outcome measured
Postoperative Blood Loss
1 sites across 1 states
Michigan1

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Eligibility criteria

Inclusion

1\. All adult (18 years old or older) hip fracture patients presenting with an acute hip fracture and undergoing operative fixation
  • Postoperative Blood TransfusionUp to two weeks

    Patient receives a blood transfusion during their postoperative stay in the hospital

  • Overall Blood LossUp to two weeks

    Calculate the difference in postoperative blood loss between groups