Understanding Ultrasound for Pulmonary Embolism in the ER

This study is looking at how a special type of ultrasound, called point-of-care echocardiography, can help doctors in the emergency room (ER) predict if patients with acute pulmonary embolism (blood clot in the lung) might have serious problems. The ultrasound checks for signs of strain on the right side of your heart. Researchers want to see if this ultrasound can accurately predict bad outcomes within 5 days of coming to the ER. They are also exploring if combining the ultrasound results with a risk score called the Pulmonary Embolism Severity Index (PESI) can give an even better prediction. You could join if you are 18 or older, have an acute pulmonary embolism diagnosed in the ER, and can give your consent. The study aims to enroll 250 participants.

Study design
This is an observational study, meaning researchers will watch and collect information without giving new treatments. It plans to include 250 participants.
What's involved
You would undergo a point-of-care echocardiography when you arrive at the ER. Your health will be monitored for adverse events within 5 days.
Compensation
Not stated in the trial record.
Follow-up
Your health will be assessed for adverse events within 5 days of presentation/enrollment.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT05050617

Point-of-Care Ultrasound in Predicting Adverse Outcomes in Emergency Department Patients With Acute Pulmonary Embolism

Recruiting
Not specifiedAges 18+Observational
WellSpan Health
~250 participants
Updated 2026-06-03 on ClinicalTrials.gov
What's tested:Point-of-care echocardiography

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Adverse Events at 5 days
Measured over Within 5 days of presentation/enrollment
Pulmonary Embolism

NCT05050617

Where you'd take part

This study runs at 1 site. They're the same protocol — you choose where, and that choice sets who your contact draft is addressed to.

  • Wellspan York Hospital

    York, Pennsylvaniastudy coordinator listed

    Recruiting

Sites open and close at different times, so the status above is per site — it can differ from the study's overall status.

  • Brent A Becker, MD · PRINCIPAL_INVESTIGATOR · WellSpan Health

Opens a ready-to-send draft in your own email app — review before sending.

Want this trial checked against your situation?

Add a private profile and we'll compare every criterion below against your situation — and tell you which ones are met, uncertain, or excluding.

Check eligibility for this trial ~2 min · HIPAA-protected · delete anytime
Eligibility criteria

Inclusion

Age \>= 18 years of age
ED diagnosis of acute pulmonary embolism with identification on CT imaging

Exclusion

Age \<18 years of age
Inability to provide informed consent
Incarceration
Current PE previously diagnosed prior to index ED visit
  • Adverse Events at 5 daysWithin 5 days of presentation/enrollment

    Composite of recurrent/worsening VTE (including PE or DVT), new cardiac dysrhythmia, major bleeding, return to the ED, death or need for critical interventions (including advanced cardiac life support, advanced respiratory support, vasopressor support, thrombolysis or new oxygen requirement occurring after initial presentation) occurring within 5 days of acute PE diagnosis