Comparing Synthetic Mammography and Full-Field Digital Mammography

This study is comparing two types of breast imaging: synthetic mammography (SM) and full-field digital mammography (FFDM). Researchers want to see how these methods compare in interpreting images and their overall performance. Digital breast tomosynthesis (DBT) is an advanced mammography technique, and synthetic mammography is a 2D image created from DBT data without extra radiation. The study aims to understand the benefits of synthetic mammography. You may be able to join if you are a woman aged 18 or older and are a consecutive case at a breast imaging center. The study will look at medical records and past imaging results to see how well synthetic mammography works compared to full-field digital mammography over an average of one year.

Study design
This is an observational study involving 750 women. It compares synthetic mammography with full-field digital mammography.
What's involved
Your medical records and past imaging examinations will be reviewed. No other procedures or visits are specified.
Compensation
Not stated in the trial record.
Follow-up
The primary endpoint is measured through study completion, an average of 1 year.

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NCT05056818

Comparison of Synthetic Mammography Versus Full-Field Digital Mammography in Image Interpretation and Performance Metrics

Recruiting
Not specifiedAges 18+Observational
M.D. Anderson Cancer Center
~750 participants
Updated 2026-04-16 on ClinicalTrials.gov
What's tested:Electronic Health Record Review

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
To analyze the impact of synthetic mammography (SM), as compared with full-field digital mammography (FFDM
Measured over through study completion, an average of 1 year
Breast Carcinoma
1 sites across 1 states
Texas1
  • Ray C Mayo · PRINCIPAL_INVESTIGATOR · M.D. Anderson Cancer Center

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Eligibility criteria

Inclusion

Female
Age 18 or older
Consecutive cases in breast imaging center

Exclusion

Cases demonstrate administrative or technical errors (e.g. missing views, labeling inconsistent with report, etc.)
  • To analyze the impact of synthetic mammography (SM), as compared with full-field digital mammography (FFDMthrough study completion, an average of 1 year