Understanding Immune Responses to Vaccines for COVID-19 and Other Infections

This observational study aims to understand how your immune system responds to vaccines for infections like SARS-CoV-2 (the virus that causes COVID-19) and other emerging diseases. Researchers want to learn why the protective effects of these vaccines might decrease over time. You may be eligible if you are a healthy adult, aged 18 or older, and are scheduled to receive a new vaccine or a booster shot for SARS-CoV-2 or another emerging infection. The study will track your immune responses over time by collecting blood samples. The goal is to better understand how these vaccines work and how long their protection lasts. The current recruitment status is unclear.

Study design
This is an observational study planning to enroll up to 1200 participants. It will follow individuals who are receiving vaccines for SARS-CoV-2 or other emerging infections.
What's involved
You will have up to 8 study visits over 1 year, each lasting less than 2 hours. At each visit, you will provide blood samples.
Compensation
Not stated in the trial record.
Follow-up
Participants will be followed throughout the study to characterize their immune responses to vaccination.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT05078905

Vaccine Responses to SARS-CoV-2 and Other Emerging Infectious Diseases

Active, Not Recruiting
Not specifiedAges 18+Observational
National Institute of Allergy and Infectious Diseases (NIAID)
~103 participants
Updated 2026-07-30 on ClinicalTrials.gov

At a glance

Recruiting sites
0 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Characterize longitudinal serologic and cellular responses to vaccination to SARS-CoV-2 and other emerging infections.
Measured over throughout
COVID-19
Vaccination
Healthy Volunteer
1 sites across 1 states
Maryland1
  • Susan L Moir, Ph.D. · PRINCIPAL_INVESTIGATOR · National Institute of Allergy and Infectious Diseases (NIAID)

This trial hasn't published a contact. View it on ClinicalTrials.gov

  • Characterize longitudinal serologic and cellular responses to vaccination to SARS-CoV-2 and other emerging infections.throughout

    Establish immunologically well characterized cohorts of primary and secondary vaccinated individuals.