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Understanding Brain Function for Hand Movement Accuracy

This study aims to understand how different parts of the brain work together to keep your hand movements accurate, a process called sensorimotor learning. Researchers are using a technique called Theta burst transcranial magnetic stimulation (cTBS), which delivers gentle magnetic pulses to specific areas of the head, to see how it affects this learning. The goal is to learn more about how the brain adapts to changes in the environment, which could eventually help improve rehabilitation for people with brain injuries. You may be able to join if you are between 18 and 45 years old and right-handed. The main way they will measure success is by looking at how your sensory perception (how you feel things) realigns after one day. The current status of this study is unclear.

Study design
This interventional study plans to enroll 300 participants. You would be randomly assigned to receive either real or sham (inactive) continuous theta burst TMS (cTBS).
What's involved
Not specified in the trial record.
Compensation
Not stated in the trial record.
Follow-up
Your sensory realignment will be measured at 1 day after the intervention.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT05079516

Neural Basis of Sensory Learning: Brain Regions

Recruiting
NAAges 18–45InterventionalBasic science
Indiana University
~300 participants
Updated 2026-05-04 on ClinicalTrials.gov
What's tested:Theta burst transcranial magnetic stimulation

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Realignment
Measured over 1 day

Conditions

Basic Science

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Healthy Volunteers

NCT05079516

Where you'd take part

This study runs at 1 site. They're the same protocol — you choose where, and that choice sets who your contact draft is addressed to.

  • Indiana University Bloomington

    Bloomington, Indianastudy coordinator listed

    Recruiting

Sites open and close at different times, so the status above is per site — it can differ from the study's overall status.

Study leadership

  • William P Hetrick, PhD · PRINCIPAL_INVESTIGATOR · Indiana University, Bloomington

Who to contact

William P Hetrick, PhD
[email protected]
8128552620
Email the study team

Opens a ready-to-send draft in your own email app — review before sending.

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Eligibility criteria

Inclusion

Potential subjects must be between the ages of 18-45 years old and right-handed. Aging has been shown to affect the morphology of sensory and motor nerves, conduction velocities of nerves, and number of motor neurons in the spinal cord; to avoid these confounding factors we will only examine younger-to middle-aged adults.
There are differences in cortical function and corticospinal projections such that testing the right arm of a right-handed individual is not necessarily equivalent to testing the left arm of a left-handed individual. To eliminate this confound, we will only test right-handed individuals. All these factors will be determined with the initial screening questions.
Covid has been found to have neurological effects in some people, but mostly the effects on sensorimotor control and neurophysiology are unknown. So we want to reduce the chances of inadvertently testing subjects who have covid. We will therefore only include individuals who are fully vaccinated (2+ weeks past their final vaccine dose) or have a negative Covid test within 4 days of testing. We will further only include individuals who report being free of Covid symptoms in week preceding testing.

What this trial measures

  • Realignment1 day

    Measured by comparing where the subject points on a touchscreen when indicating perceived position of visual and proprioceptive targets early vs. late in the behavioral task.