Locomotor Recovery and Compensation Post-stroke (LRC) Study

This study is looking at how people recover their ability to walk after a stroke, and how their bodies might adapt or compensate. It's testing a type of training called high-intensity training, which focuses on stepping in different situations. You might be able to join if you've recently had your first stroke, have weakness on one side of your body (unilateral hemiparesis), are currently in inpatient rehabilitation, and can follow simple instructions. The researchers want to see if this training improves your walking speed, measured at 15 days, 1 month, and 2 months after your stroke. The current status of this study is unclear, and it plans to enroll 150 participants.

Study design
This is an interventional study, meaning participants will receive a specific treatment. It plans to enroll 150 participants.
What's involved
Participants will receive approximately 10 weeks (about 30 sessions) of high-intensity training.
Compensation
Not stated in the trial record.
Follow-up
Your walking speed will be measured at 15 days, 1 month, and 2 months after your stroke.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT05081713

Locomotor Recovery and Compensation Post-stroke (LRC)

Recruiting
NAAges 18–85InterventionalTreatment
Indiana University
~150 participants
Updated 2026-03-05 on ClinicalTrials.gov
What's tested:high-intensity training focused on stepping in variable contexts

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Gait speed
Measured over 15 days post-stroke
+13 more outcomes measured
Stroke

NCT05081713

Where you'd take part

This study runs at 1 site. They're the same protocol — you choose where, and that choice sets who your contact draft is addressed to.

  • Rehabilitation Hospital of Indiana

    Indianapolis, Indianastudy coordinator listed

    Recruiting

Sites open and close at different times, so the status above is per site — it can differ from the study's overall status.

  • Thomas G Hornby · PRINCIPAL_INVESTIGATOR · Indiana University

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Eligibility criteria

Inclusion

individuals early post-stroke (\<15-30 days)
first ever stroke
unilateral hemiparesis
currently receiving inpatient rehabilitation
ability to follow 1-step commands
provision of informed consent
medical clearance from the rehabilitation physician to participate. \\

Exclusion

uncontrolled cardiovascular, metabolic or respiratory disease that limits exercise participation (e.g., congestive heart failure, resting blood pressure \> 200/110 mmHg, uncontrolled diabetes, end-stage renal disease)
absolute criteria for termination of exercise testing during initial and repeated ECG testing during graded exercise testing using ACSM guidelines .
other orthopedic or neurological disorder that limited walking prior to stroke
  • Gait speed15 days post-stroke

    Walking speed over 6 m

  • Gait speed1 month

    Walking speed over 6 m

  • Gait speed2 months,

    Walking speed over 6 m

  • Gait speed4 months,

    Walking speed over 6 m

  • Gait speed6 months,

    Walking speed over 6 m

  • Gait speed9 months,

    Walking speed over 6 m

  • Gait speed12 months

    Walking speed over 6 m

  • Walking distance15 days post-stroke,

    Distance covered over 6 min

  • Walking distance1 month,

    Distance covered over 6 min

  • Walking distance2 months,

    Distance covered over 6 min

  • Walking distance4 months,

    Distance covered over 6 min

  • Walking distance6 months,

    Distance covered over 6 min

  • Walking distance9 months,

    Distance covered over 6 min

  • Walking distance12 months

    Distance covered over 6 min