Improving Visual Field Deficits with Noninvasive Brain Stimulation

This study is looking for people aged 18 to 80 who have visual field deficits (VFD), which means a part of their vision is missing, often due to a stroke or brain injury. Researchers are testing if combining noninvasive brain stimulation called transcranial random noise stimulation (tRNS) with visual training can help improve vision. tRNS uses a device placed on the scalp to deliver a very mild electrical current to the visual part of the brain. The visual training involves looking at moving images on a computer screen or in a virtual reality headset. The main goal is to see if these treatments can improve your ability to see moving objects after 10 days and again after 6 months. This is a pilot study, meaning it's an early step to refine a rehabilitation approach for VFD.

Study design
This is a randomized pilot study with 24 participants. It compares transcranial random noise stimulation (tRNS) and visual training to sham stimulation (a fake treatment) and visual training.
What's involved
You would receive either real or sham transcranial random noise stimulation for 20-30 minutes, along with visual training using a computer or virtual reality headset. The study measures changes in your vision after 10 days and again after 6 months.
Compensation
Not stated in the trial record.
Follow-up
Your visual abilities will be measured after 10 days of training/stimulation and again after 6 months of training/stimulation.

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NCT05085210

Improving Visual Field Deficits With Noninvasive Brain Stimulation

Recruiting
NAAges 18–80InterventionalTreatment
Beth Israel Deaconess Medical Center
~24 participants
Updated 2026-03-04 on ClinicalTrials.gov
What's tested:transcranial random noise stimulation (tRNS)Computer Based Visual TrainingSham stimulationVirtual Reality Based Visual Training

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Visual Motion Discrimination Change
Measured over After 10 days training/stimulation and after 6 months training/stimulation
Visual Field Defect, Peripheral
Stroke
Visual Impairment
Hemianopsia
Quadrantanopia
Cortical Blindness
Visual Field Defect Homonymous Bilateral
Occipital Lobe Infarct
Visual Fields Hemianopsia
1 sites across 1 states
Massachusetts1
  • Lorella Battelli, PhD · PRINCIPAL_INVESTIGATOR · Beth Israel Deaconess Medical Center

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Eligibility criteria

Inclusion

Ischemic stroke patients will be either subacute (within 6 months of their stroke) or chronic (more than 6 months)
Hemorrhagic stroke patients will be chronic only (greater than 6 months) 4. Must demonstrate a clear deficit in either simple or complex visual perception in portions of their visual field as measured by visual perimetry. 5. Imaging evidence that the stroke is primarily affecting the visual cortex. 6. Willing and able to participate in the study protocol and to comply with study procedures.
  • Visual Motion Discrimination ChangeAfter 10 days training/stimulation and after 6 months training/stimulation

    Change in the motion discrimination computer or VR task after training within the blind visual field