Observational Study: Visually Evoked Potentials in Hearing Loss

This study is looking at how a test called "P300 Visually evoked potential" can be used for people with hearing loss. This test measures your brain's response, or "brain waves," to specific visual images. Researchers want to see if this test, which is already used in other medical areas, can help them understand and improve treatments for hearing loss. You may be able to join if you are 18 or older and have sensorineural hearing loss. The study aims to enroll 100 participants. The main goal is to measure differences in how quickly and strongly your brain responds to visual stimuli, specifically the P300 wave, within 30 minutes of the test.

Study design
This is an observational study aiming to enroll 100 participants. It is not specified if it is randomized or blinded.
What's involved
You will have two appointments. The first involves a vision test and then wearing electrodes on your scalp for about an hour while watching images. The second appointment includes an auditory test, a cognitive/mood assessment, and a sound quality survey if you have a cochlear implant.
Compensation
Not stated in the trial record.
Follow-up
The primary measurements for brain responses are taken at 30 minutes during the testing session. No further follow-up is specified.

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NCT05107466

Quantification of Visually Evoked Cortical Potentials in Individuals With Hearing Loss

Recruiting
Not specifiedAges 18+Observational
Dartmouth-Hitchcock Medical Center
~100 participants
Updated 2025-10-29 on ClinicalTrials.gov
What's tested:P300 Visually evoked potential

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Difference in mean VEP latency as measured by onset time of the P300 wave from time of stimuli presentation.
Measured over 30 minutes
+1 more outcome measured
Sensorineural Hearing Loss
Hearing Loss
1 sites across 1 states
New Hampshire1
  • James E Saunders, MD · PRINCIPAL_INVESTIGATOR · Department of Surgery, Otolaryngology section, Dartmouth Hitchcock Medical Center

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  • Difference in mean VEP latency as measured by onset time of the P300 wave from time of stimuli presentation.30 minutes

    Difference in P300 VEP latency to odd ball paradigm visual stimuli in individuals with hearing loss and normal hearing controls. Differences in VEP latency will be measured by recording onset time of the P300 signal from time of stimuli presentation.

  • Difference in mean VEP amplitude as measured by the maximum voltage reached by the P300 wave after presentation of stimulus before returning back to zero.30 minutes

    Difference in mean VEP amplitude to odd ball paradigm visual stimuli in individuals with hearing loss and normal hearing controls. Differences in VEP amplitude will be measured by recording maximum voltage reached by the P300 wave after presentation of stimulus before returning back to zero.