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NCT05110833

Dose Responsiveness as a Measure of Clinical Effectiveness During Neuromonitored Spine Surgery

Enrolling by Invitation
Not specifiedAges 18+Observational
Allina Health System
~500 participants
Updated 2026-01-30 on ClinicalTrials.gov

At a glance

Recruiting sites
0 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Nature of changes in free-run smooth muscle EMG under varying surgical and anesthetic conditions
Measured over 1 day
+2 more outcomes measured

Conditions

Intervertebral Disc Degeneration
Intervertebral Disc Displacement
Spinal Curvatures
Spinal Stenosis
Spondylitis
Spondylosis

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Where it's being run

1 sites across 1 states
Minnesota1

Study leadership

  • Stanley A Skinner, MD · PRINCIPAL_INVESTIGATOR · Allina Health

Who to contact

This trial hasn't published a contact. View it on ClinicalTrials.gov

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Eligibility criteria

Inclusion

Must be 18+ years old
Patients must be undergoing cervical and/or thoracic spine surgical procedure at Abbott Northwestern Hospital in Minneapolis, MN

Exclusion

Patients who are non-English speakers
Patients with ongoing psychiatric concerns are excluded
Patients unwilling to be contacted for a 6-month follow-up

What this trial measures

  • Nature of changes in free-run smooth muscle EMG under varying surgical and anesthetic conditions1 day

    Free-run smooth muscle EMG will be monitored continuously throughout the duration of surgery. Any changes in the EMG, as indicated by fluctuation in amplitude and/or frequency, will be recorded.

  • Nature of changes in free-run smooth muscle EMG resulting from the inadvertent effect of intraoperative monitoring stimulation and recording.1 day

    Smooth muscle EMG in response to stimulations and recordings will be monitored. Any changes in the EMG, as indicated by fluctuation in amplitude and/or frequency, will be recorded.

  • The believable and repeatable smooth muscle EMG response, if any, measured by amplitude and frequency after deliberate spinal/extra-spinal neural stimulations.1 day