Observational Study of Cryoanalgesia for Post-Operative Pain

This study is looking at how well a treatment called cryoanalgesia works for managing pain after surgery. Cryoanalgesia uses a device called the AtriCure Cryo Nerve Block to freeze intercostal nerves (nerves between your ribs) to reduce pain. Researchers want to see how effective and safe this treatment is over a period of up to five years. You might be able to join if you are 12 years or older and are scheduled to have or have already had this cryoablation procedure, or a similar procedure without cryoablation. This is an observational study, meaning researchers will collect information about your experience rather than giving you a new treatment.

Study design
This is an observational study that plans to include 5000 participants. It will collect information both from past records and from people currently undergoing treatment.
What's involved
Not specified in the trial record.
Compensation
Not stated in the trial record.
Follow-up
Participants will be followed from their enrollment date for up to 5 years after their procedure to assess the treatment's effectiveness and safety.

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NCT05110989

A Multicenter Patient Registry on Outcomes From Cryoanalgesia of the Intercostal Nerves

Recruiting
Not specifiedAges 12+Observational
AtriCure, Inc.
~5,000 participants
Updated 2026-06-29 on ClinicalTrials.gov
What's tested:AtriCure Cryo Nerve Block (cryoNB) Device Family

At a glance

Recruiting sites
10 of 11 listed sites are recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Efficacy of cryo nerve block to generate cryoanalgesia as post operative pain management
Measured over From enrollment to 5 years after date of index procedure
+1 more outcome measured
Post Operative Pain
11 sites across 10 states
Florida2
Maryland1
Missouri1
New Hampshire1
Ohio1
Texas1
Austria1
Belgium1
  • Curits Quinn, MD · PRINCIPAL_INVESTIGATOR · Elliot Hospital

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  • Efficacy of cryo nerve block to generate cryoanalgesia as post operative pain managementFrom enrollment to 5 years after date of index procedure

    Collect pain score to assess the effect of cryoanalgesia effect with a follow up duration of up to 5 years.

  • Safety of cryo nerve block to generate cryoanalgesia as post operative pain managementFrom enrollment to 5 years after date of index procedure

    Collect adverse events occurred during and post operation to assess the safety of the cryo nerve block procedure.