Understanding Gut Sensations in Anorexia Nervosa

This study is looking into how people with anorexia nervosa (AN) experience "gut sensations" and if these sensations are linked to the challenges of the disorder. Researchers are using a special device called a Vibrant capsule, which delivers mechanical vibrations, to understand these sensations better. The study aims to enroll 150 women between 15 and 40 years old. To join, you need to have a Body Mass Index (BMI) of 18.5 or higher, be able to walk on your own, have a smartphone with a data plan, and speak English. For women of childbearing age, specific birth control methods are required. The main goals are to measure how accurately you sense internal body signals (interoceptive precision), your existing beliefs about these sensations (interoceptive prior), and how you learn about them (learning rate) at the start of the study. The current recruitment status is unclear.

Study design
This is an interventional study with a planned enrollment of 150 women. It is not specified if it is randomized or blinded.
What's involved
Not specified in the trial record.
Compensation
Not stated in the trial record.
Follow-up
The primary endpoints are measured at baseline, so long-term follow-up after treatment is not specified.

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NCT05111977

Gastrointestinal Interoception in Anorexia Nervosa

UNKNOWN
NAAges 15–40InterventionalBasic science
Laureate Institute for Brain Research, Inc.
~150 participants
Updated 2024-05-10 on ClinicalTrials.gov
What's tested:Vibrant capsule

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Interoceptive precision
Measured over At baseline
+4 more outcomes measured
Anorexia Nervosa
1 sites across 1 states
Oklahoma1

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  • Interoceptive precisionAt baseline

    Interoceptive sensory precision

  • Interoceptive priorAt baseline

    Interoceptive prior expectaiton

  • Learning rateAt baseline

    Interoceptive learning rate

  • Evoked response potentialAt baseline

    Electroencephalogram (EEG) evoked response amplitude within 700 millisecond period following vibration onset

  • ElectrogastrogramAt baseline

    Stomach electrogastrogram (EGG) power in bradygastria, normogastria, tachygastria and total power bands