Post Mortem Tissue Donation for Pediatric Cancer Research

This study is collecting tissue from children with cancer and non-cancerous tumors after they have passed away. This is an observational study, meaning researchers are collecting information without giving any new treatments. The goal is to use these donated tissues to create new models in the lab, like mouse models and cell cultures, to better understand pediatric cancers. These models will help researchers study the diseases and test new drugs in the future. To join, families must provide signed consent for post-mortem tissue donation and autopsy. The study aims to successfully collect these tissues for up to 5 years from the time of donation. The current recruitment status is unclear.

Study design
This is an observational study planning to enroll 150 participants. It is not testing a new drug or treatment.
What's involved
Participants would have their post-mortem tissue collected during an autopsy after consent is obtained.
Compensation
Not stated in the trial record.
Follow-up
The primary goal is the procurement of tissue, measured for up to 5 years from procurement.

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NCT05120518

Post Mortem Tissue Donation of Pediatric Tumor Tissues and Cells

Recruiting
Not specifiedAll AgesObservational
Ann & Robert H Lurie Children's Hospital of Chicago
~150 participants
Updated 2026-06-03 on ClinicalTrials.gov
What's tested:Collection of post mortem tissue donation

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Procurement of pediatric cancer and non-cancer tumor tissue during autopsy with signed consent
Measured over Up to 5 years from procurement
Pediatric Cancer
1 sites across 1 states
Illinois1
  • Angela Waanders, MD · PRINCIPAL_INVESTIGATOR · Ann & Robert H Lurie Children's Hospital of Chicago

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Eligibility criteria

Inclusion

Pediatric patients with cancer and non-cancer tumor types (solid, liquid, neuro-oncology)
Signed consent for post mortem tissue donation and autopsy

Exclusion

Signed consent for post mortem tissue donation and autopsy not obtained
  • Procurement of pediatric cancer and non-cancer tumor tissue during autopsy with signed consentUp to 5 years from procurement

    Procurement of pediatric cancer and non-cancer tumor tissue during autopsy with signed consent. Tissue will be collected through a research tissue collection autopsy of the original tumor and other sites that are appropriate. Samples of both tumor and normal cells will be collected in addition to body fluids such as cerebrospinal fluid (CSF), blood, bone marrow, and skin biopsies for genomic testing.