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Observational Study on Adenoma Detection Rate in Colonoscopy

This study is looking at whether the 'overall adenoma detection rate' (ADR) can be a reliable way to measure how well doctors find polyps (adenomas) during a colonoscopy. Currently, doctors often use the 'screening ADR,' which only looks at colonoscopies done for screening. This study will compare that to an 'overall ADR' that includes colonoscopies done for screening, follow-up (surveillance), or to investigate symptoms (diagnostic). They want to see if these different ways of calculating ADR are similar enough. You might be able to join if you are between 50 and 80 years old and are having a colonoscopy. The main goal is to measure the adenoma detection rate within 7 days. The study status is currently unclear.

Study design
This is an observational study involving about 2700 participants. It is not a randomized trial, meaning participants are not assigned to different treatment groups.
What's involved
Not specified in the trial record.
Compensation
Not stated in the trial record.
Follow-up
The primary endpoint, adenoma detection rate, is measured at 7 days.

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NCT05125939

Can Overall Adenoma Detection Rate Replace Screening Adenoma Detection Rate ? Multicenter Study

Recruiting
Not specifiedAges 50–80Observational
Evergreen General Hospital, Taiwan
~2,700 participants
Updated 2025-08-07 on ClinicalTrials.gov
What's tested:Comparison of ADR

At a glance

Recruiting sites
1 of 6 listed sites are recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Adenoma detection rate
Measured over 7 days

Conditions

Adenoma Detection Rate
Colonoscopy

Explore related trials

Colorectal Adenoma

Where it's being run

6 sites across 2 states
Taiwan5
California1

Study leadership

  • Chi-Liang Cheng · PRINCIPAL_INVESTIGATOR · Evergreen General Hospital, Taoyuan, Taiwan

Who to contact

Chi-Liang Cheng
[email protected]
0919768058
Email the study team

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Do you actually qualify for this trial?

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Eligibility criteria

Inclusion

consecutive patients aged ≥50 years undergoing colonoscopy are eligible for enrollment.

Exclusion

high risk family history of colorectal cancer (CRC) e.g., familial adenomatous polyposis, hereditary non-polyposis CRC syndrome, multiple first degree relatives with CRC, or a single first degree relative with CRC at \<60 years
serrated polyposis syndrome
inflammatory bowel disease
colonoscopy to remove a large neoplastic polyps
obstructive lesions of the colon
gastrointestinal bleeding
current participation in other studies
hospitalized patients
mental retardation
pregnancy
refusal to provide a written informed consent.

What this trial measures

  • Adenoma detection rate7 days

    The proportion of participants undergoing a complete colonoscopy who have one or more adenomas detected