Prebiotics to Improve Gut Health After Stem Cell Transplant
This study is exploring whether a prebiotic called resistant starch (Bob's Red Mill® potato starch) can improve the diversity of your gut microbiome (the community of bacteria in your intestines) after an autologous cellular therapy (a type of stem cell transplant using your own cells). A healthier gut microbiome has been linked to better outcomes for people with multiple myeloma or lymphoma. You would receive either resistant starch or a placebo (maltodextrin) mixed into a food item daily for about 10 days before your stem cell infusion and continue until your white blood cell count recovers. The study aims to see if participants take at least 70% of their scheduled doses. This study is for adults aged 19 and older with multiple myeloma or certain types of lymphoma who are undergoing an autologous stem cell transplant. About 30 people are expected to join.
- Study design
- This is a randomized, double-blind study, meaning you would be randomly assigned to receive either resistant starch or a placebo, and neither you nor your doctors would know which you are receiving. It plans to enroll 30 participants.
- What's involved
- You would take a dietary supplement mixed into food daily for approximately 10 days before your stem cell infusion and continue until your white blood cell count recovers. Fecal samples will be collected at four different times.
- Compensation
- Not stated in the trial record.
- Follow-up
- The primary goal is measured at 35 days, which suggests follow-up for at least this duration.
AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.
Study Using Prebiotics to Improve Gut Microbiome Diversity After Autologous Cellular Therapy
At a glance
Conditions
Where it's being run
1 sites across 1 statesStudy leadership
- Christopher R D'Angelo, MD · PRINCIPAL_INVESTIGATOR · University of Nebraska
Who to contact
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What this trial measures
- Percentage of subjects who adhere to >70% of scheduled doses of the intervention35 Days
To understand the feasibility of the intervention in the proposed study population, the percentage of subjects who adhere to \>70% of scheduled doses will be calculated