Intraoperative Radiation Therapy for Pancreatic Cancer
This study is looking at a treatment called Intraoperative Radiation Therapy (IORT) for people with pancreatic cancer that can be removed by surgery. You would first receive standard chemotherapy and Stereotactic Body Radiation Therapy (SBRT). Then, during surgery to remove the tumor, you would receive a single dose of radiation (15 Gy) directly to the area where the tumor was. Doctors want to see how safe this treatment is by checking for any side effects within three months after surgery. This study is for adults over 18 with certain types of pancreatic cancer and good general health. The study plans to enroll 25 participants, but its current status is unclear.
- Study design
- This is an interventional study, meaning participants will receive a specific treatment. It is designed to enroll 25 participants.
- What's involved
- You would receive standard chemotherapy and SBRT, followed by surgery where you would also receive a single dose of IORT. Your health would be monitored for three months after surgery.
- Compensation
- Not stated in the trial record.
- Follow-up
- Your acute post-operative toxicity will be measured at 3 months after the intervention.
AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.
Intraoperative Radiation Therapy After Stereotactic Body Radiation Therapy and Chemotherapy in Treatment of Pancreatic Adenocarcinoma
At a glance
Conditions
Where it's being run
1 sites across 1 statesStudy leadership
- Amol Narang, MD · PRINCIPAL_INVESTIGATOR · JHU, School of Medicine, SKCCC
Who to contact
This trial hasn't published a contact. View it on ClinicalTrials.gov
What this trial measures
- Acute post-operative toxicity of targeted IORT3 months
To evaluate acute post-operative toxicity of IORT targeted to the TV in patients with non-metastatic PDAC undergoing surgical resection after neoadjuvant multi-agent chemotherapy and SBRT.