Weight Management Study: AVOID and RESIST Strategies

This study is looking at new ways to help people with overweight or obesity manage their weight. It tests two approaches: AVOID, which helps you change your home food environment and get healthy groceries delivered, and RESIST, which uses coaching and games to help you control impulses around food. All participants will also join a commercial weight management program (WW). Researchers want to see how these strategies affect your body mass index (BMI) over 12 months. You might be able to join if you are 18 or older, have a BMI between 25-45 kg/m2, and can read and speak English. The study aims to enroll about 500 people, but its current recruitment status is unclear.

Study design
This is an interventional study with approximately 503 participants. All participants will receive the WW program and will be randomly assigned to one of four groups, which may include AVOID, RESIST, or both.
What's involved
You would receive 6 months of coaching via Zoom, email, or text. You will also have assessments at the start, 6 months, and 12 months. If you live with another eligible household member, they would complete three brief assessments over 12 months.
Compensation
Not stated in the trial record.
Follow-up
Your BMI will be measured at 6 months and 12 months after starting the study.

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NCT05143931

Avoid and Resist Strategies for Weight Management

Recruiting
NAAges 14+InterventionalTreatment
Cedars-Sinai Medical Center
~503 participants
Updated 2026-02-17 on ClinicalTrials.gov
What's tested:Home food environment and grocery delivery (AVOID)Inhibitory control training (RESIST)WW

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Change in BMI from baseline to 12 months.
Measured over Baseline, 6-month, 12-month
Obesity
Overweight
1 sites across 1 states
California1
  • Sarah-Jeanne Salvy, PhD · PRINCIPAL_INVESTIGATOR · Cedars-Sinai Medical Center

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Eligibility criteria

Inclusion

Age 18 years or older
BMI between 25-45 kg/m2
Read, write, and speak English with acceptable visual acuity
Has a household member (≥ 14 years) willing to complete three brief assessments over 12 months\* \*Only applies to individuals who indicate they are cohabitating with at least one eligible household member
14-years-old
Parent consent for children \<18-years-old
Willingness to complete assessments / measurements

Exclusion

Currently enrolled in weight loss interventions or undergoing bariatric surgery
Pregnant women
Individuals for whom weight loss may be contraindicated (e.g., unstable coronary artery disease, end-stage disease, active cancer treatment, uncontrolled insulin-dependent diabetes, portal hypertension, drug/alcohol abuse)
Individuals with severe cognitive delays or visual/hearing impairment
Individuals who are unable or unwilling to complete the study assessments / measurements
≤ 14-years-old
Individuals who are unable or unwilling to complete the study assessments / measurements
  • Change in BMI from baseline to 12 months.Baseline, 6-month, 12-month

    BMI will be calculated by aggregating participants' self-reported height in meters and weight in kilograms at baseline, 6- and 12-months.