This study is looking at how the amount of phosphate in your diet affects your ability to exercise and the amount of fat around your organs (visceral adiposity). Researchers want to see if lowering your dietary phosphate intake can improve how your muscles use energy and how much oxygen you use during exercise. You would take either Sodium Phosphate capsules or Sodium Chloride capsules daily for 4 weeks each, with a break in between. The study is for healthy adults aged 18 to 80 who do not have diabetes, kidney disease, or heart disease. The main goal is to measure your oxygen uptake during peak exercise after 4 weeks of treatment. The study aims to enroll 124 participants.

Study design

This is a randomized crossover study, meaning participants will receive both treatments at different times. It plans to enroll 124 participants.

What's involved

You would follow a low phosphate diet for 8 weeks and take capsules daily for two 4-week periods. Your phosphate intake will be estimated by food recall, and your oxygen uptake will be measured during exercise.

Compensation

Not stated in the trial record.

Follow-up

Your oxygen uptake during peak exercise will be measured at 4 weeks after starting each treatment period.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.