Observational Study on Laryngeal Dystonia and Voice Tremor
This study aims to better understand laryngeal dystonia (a voice disorder causing strained or interrupted speech) and voice tremor (a shaky voice). Researchers will use various clinical assessments, including recordings of your voice, breathing, and throat muscles, as well as real-time MRI scans. The goal is to identify clear differences between these conditions, which often get confused, to improve diagnosis and treatment. You might be able to join if you are between 18 and 80 years old, a native English speaker, right-handed, and have laryngeal dystonia or voice tremor. Healthy individuals without neurological, psychiatric, or ear, nose, and throat problems can also participate as controls. The study is looking for 165 participants, but its current status is unclear.
- Study design
- This is an observational study involving 165 planned participants. It aims to characterize clinical features of laryngeal dystonia and voice tremor.
- What's involved
- Participants will undergo acoustic, aerodynamic, respiratory kinematic, nasoendoscopic, and laryngeal EMG recordings, as well as real-time MRI of the upper airway.
- Compensation
- Not stated in the trial record.
- Follow-up
- Differences in voice symptoms will be measured at 5 years.
AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.
Characterization of Clinical Phenotypes of Laryngeal Dystonia and Voice Tremor
At a glance
Conditions
Where it's being run
1 sites across 1 statesStudy leadership
- Kristina Simonyan, MD, PhD · STUDY_DIRECTOR · Massachusetts Eye and Ear
Who to contact
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What this trial measures
- Differences in voice symptoms5 years
Clinical phenotypic features and speech structure kinematics that distinguish between laryngeal dystonia and voice tremor