Music Therapy for Patients With Alzheimer's Disease
This study is exploring if virtual music therapy can help people with mild cognitive impairment (MCI) or early Alzheimer's disease (AD). You would receive two 30-minute live online music therapy sessions each week for 8 weeks, led by a certified music therapist. The researchers want to see if these sessions can improve your memory, mood, and thinking abilities. They will measure changes in your autobiographical memory (memories about your own life) and neuropsychiatric symptoms (like anxiety or agitation) to see if the therapy is helpful. The study aims to enroll 60 participants.
- Study design
- This is an interventional study planning to enroll 60 participants with mild cognitive impairment or early Alzheimer's disease.
- What's involved
- You would participate in two 30-minute virtual music therapy sessions per week for 8 weeks, for a total of 16 sessions. Assessments will be done before and after the 8-week treatment period.
- Compensation
- Not stated in the trial record.
- Follow-up
- Your memory and neuropsychiatric symptoms will be assessed at Baseline and again at Post-test Week 12.
AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.
Music Therapy for Patients With Alzheimer's Disease
At a glance
Conditions
Where it's being run
1 sites across 1 statesStudy leadership
- Alexander Pantelyat, MD · PRINCIPAL_INVESTIGATOR · Department of Neurology, Johns Hopkins School of Medicine
Who to contact
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Do you actually qualify for this trial?
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Inclusion
Exclusion
What this trial measures
- Change in autobiographical memory level as assessed by Autobiographical Memory Test (AMT)Baseline and Post-test Week 12
AMT is used to assess the degree of specificity of autobiographical memory. The AMT usually contains cue words of both positive and negative valence, but it is unclear whether these valences form separate factors or not. Participants are asked to generate a specific memory that happened on a particular day at least one week ago. The number of specific memories recalled on each AMT is used as the dependent variable, and a higher frequency indicates a greater autobiographical memory level. Scores are on a scale from 1 to 7, where higher scores indicate greater familiarity/imageability.
- Change in scores on neuropsychiatric symptom level as assessed by Neuropsychiatric Inventory Questionnaire (NPI-Q) (caregivers)Baseline and Post-test Week 12
The NPI-Q is designed to be a self-administered questionnaire completed by informants about patients for whom they care. Each of the 12 NPI-Q domains contains a survey question that reflects cardinal symptoms of that domain. The severity scale has scores ranging from 1 to 3 points (1=mild; 2=moderate; and 3=severe; total score range: 0 - 36) and the scale for assessing caregiver distress has scores ranging from 0 to 5 points (0=no distress; 1=minimal distress; 2=mild distress; 3=moderate distress; 4=severe distress; and 5=extreme distress; total score range: 0-60).