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NCT05161078

Improving Continuous Renal Replacement Therapy Outcomes in Neonates and Infants Through Interdisciplinary Collaboration

Enrolling by Invitation
Not specifiedAll AgesObservational
Children's Hospital Medical Center, Cincinnati
~1,000 participants
Updated 2026-03-23 on ClinicalTrials.gov
What's tested:CARPEDIEM

At a glance

Recruiting sites
0 of 9 listed sites are recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Number of CARPEDIEM filters to meet prescribed treatment length
Measured over 24 hours
+2 more outcomes measured

Conditions

Acute Kidney Injury
Chronic Kidney Diseases
Renal Dialysis

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Acute Renal FailureChronic Kidney DiseaseHemodialysis

NCT05161078

Where you'd take part

This study runs at 9 sites. They're the same protocol — you choose where, and that choice sets who your contact draft is addressed to.

  • C.S. Mott Children's Hospital

    Ann Arbor, Michiganno site contact published

  • Children's Hospital Colorado

    Aurora, Coloradono site contact published

  • Children's Hospital of Atlanta

    Atlanta, Georgiano site contact published

  • Cincinnati Children's Hospital Medical Center

    Cincinnati, Ohiono site contact published

  • Lucile Salter Packard Children's Hospital at Stanford

    Palo Alto, Californiano site contact published

  • Seattle Children's

    Seattle, Washingtonno site contact published

  • Texas Children's Hospital

    Houston, Texasno site contact published

  • The Medical College of Wisconsin

    Milwaukee, Wisconsinno site contact published

Sites open and close at different times, so the status above is per site — it can differ from the study's overall status.

Study leadership

  • Cara Slagle, MD · PRINCIPAL_INVESTIGATOR · Cincinnati Children's

Who to contact

This trial hasn't published a contact. View it on ClinicalTrials.gov

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Eligibility criteria

Inclusion

Treated with CARPEDIEM as part of standard of care at a participating institution within the United States

Exclusion

Parents/legally authorized representative unable or unwilling to provide consent

What this trial measures

  • Number of CARPEDIEM filters to meet prescribed treatment length24 hours

    Comparing actual time of treatment of each CARPEDIEM filter to the initial prescribed length of treatment at the time of filter initiation

  • Rate of patient survivalthrough hospital discharge, an average of less than 1 year

    Percent of patients treated with the CARPEDIEM who survive to hospital discharge

  • Rate of renal recoverythrough hospital discharge, an average of less than 1 year

    Excluding patients with End Stage Renal Disease (ESRD), percent of patients treated with the CARPEDIEM who recover baseline renal function as measured by liberation from dialysis and serum creatinine returning to within less than a 50% increase over baseline.