NCT05162638

Immune Profiles in Multiple Sclerosis (MS) Patients and Healthy Volunteers Through Thoracic Duct Cannulation

Enrolling by Invitation
NAAges 18–40Interventional
University of Pennsylvania
~24 participants
Updated 2026-01-09 on ClinicalTrials.gov
What's tested:thoracic duct cannulation

At a glance

Recruiting sites
0 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Safety and Tolerability
Measured over up to 21 days
+1 more outcome measured
Multiple Sclerosis
Healthy

NCT05162638

Where you'd take part

This study runs at 1 site. They're the same protocol — you choose where, and that choice sets who your contact draft is addressed to.

  • University of Pennsylvania

    Philadelphia, Pennsylvaniano site contact published

Sites open and close at different times, so the status above is per site — it can differ from the study's overall status.

  • Amit Bar-Or, MD · PRINCIPAL_INVESTIGATOR · University of Pennsylvania

This trial hasn't published a contact. View it on ClinicalTrials.gov

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Eligibility criteria

Exclusion

1\. Participants suspected of not being able or willing to cooperate or comply with study protocol requirements in the opinion of the investigator.
  • Safety and Tolerabilityup to 21 days

    Quantified as percent of the study population experiencing serious adverse event from in-and-out catherization procedure and from "indwelling" catheterization procedure

  • B Cellsup to 21 days

    Change in proportion of flow cytometry defined naïve (CD27-) and memory (CD27+) B cells in thoracic duct of patients with MS prior to and following anti-CD20 therapy with Ofatumumab