Beta-blocker Discontinuation in Heart Failure With Preserved Ejection Fraction
This study is looking at what happens when people with a type of heart failure called Heart Failure With Preserved Ejection Fraction (HFpEF) stop taking their beta-blocker medication. Researchers want to see if stopping beta-blockers changes how you feel and your quality of life. They will measure this using a questionnaire called the KCCQ-23 score. You might be able to join if you are between 50 and 80 years old, have stable HFpEF, and are currently taking a beta-blocker. The study aims to enroll 30 participants, but its current recruitment status is unclear.
- Study design
- This is a pilot study that will look at changes in 30 participants before and after stopping beta-blockers. It is an interventional study, meaning participants will receive a specific intervention.
- What's involved
- You would have two study visits over a period of about 4 weeks. The first visit is a standard clinic visit, and the second involves questionnaires and a limited echocardiogram (a heart ultrasound).
- Compensation
- Not stated in the trial record.
- Follow-up
- There is no long-term follow-up beyond the second visit, which occurs 4 weeks after stopping beta-blockers.
AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.
Beta-blocker Discontinuation in Heart Failure With Preserved Ejection Fraction
At a glance
Conditions
Where it's being run
1 sites across 1 statesStudy leadership
- Kai Chen, MD,PhD · PRINCIPAL_INVESTIGATOR · UConn Health
Who to contact
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Do you actually qualify for this trial?
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Inclusion
Exclusion
What this trial measures
- Changes in KCCQ-23 scoreBaseline and after 4 weeks of beta blocker discontinuation
Kansa city cardiomyopathy questionnaire (KCCQ-23)- self-administered, 23-item. questionnaire that quantifies physical limitations, symptoms, self-efficacy, social interference and quality of life. Scores are transformed to a range of 0-100, where higher scores reflect better health status.