Back to search results

Observational Study of Biliary Tree Cancers

This study is looking at factors that might lead to biliary tree cancers (cancers of the bile ducts and gallbladder). Researchers want to understand if things like your environment, viruses, behaviors, medical history, diet, and genetic changes play a role in developing these cancers and how they respond to treatment. You would provide tissue and blood samples, and complete a questionnaire. The main goal is to find important factors that contribute to these cancers and identify new genetic markers. This information could help doctors better understand why some people's cancer responds differently to treatments.

Study design
This is an observational study aiming to enroll 1500 participants. It includes people with cholangiocarcinoma (bile duct cancer) or gallbladder cancer, and healthy controls.
What's involved
You would complete a questionnaire that takes about 20 minutes. You would also provide blood and leftover tissue samples.
Compensation
Not stated in the trial record.
Follow-up
The primary endpoints, which are the significant factors contributing to the cancer, will be measured through study completion, an average of 1 year.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT05179486

Molecular Epidemiology of Biliary Tree Cancers

Recruiting
Not specifiedAll AgesObservational
M.D. Anderson Cancer Center
~1,500 participants
Updated 2026-04-17 on ClinicalTrials.gov
What's tested:Biospecimen CollectionQuestionnaire Administration

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Significant factors that may contribute to the etiology of biliary tree cancer
Measured over through study completion, an average of 1 year

Conditions

Cholangiocarcinoma
Malignant Digestive System Neoplasm

Explore related trials

CholangiocarcinomaGallbladder CarcinomaMalignant neoplasm of digestive system

Where it's being run

1 sites across 1 states
Texas1

Study leadership

  • Manal M Hassan · PRINCIPAL_INVESTIGATOR · M.D. Anderson Cancer Center

Who to contact

Manal M Hassan
[email protected]
713-794-5452
Email the study team

Opens a ready-to-send draft in your own email app — review before sending.

Do you actually qualify for this trial?

Add a private profile and we'll compare every criterion below against your situation — and tell you which ones are met, uncertain, or excluding.

Check eligibility for this trial ~2 min · HIPAA-protected · delete anytime
Eligibility criteria

Inclusion

Pathologically or radiologically confirmed diagnosis of CGC or GBC
With or without prior radiation or chemotherapy
All United States of America (USA) and non USA residents
No age, gender, or racial restriction
Healthy control with no current or history of cancer
Healthy controls are USA and non USA residents
Healthy controls are matched to the cases in age (5 years), gender, and race
Healthy controls are friends and spouses of patients with other than gastro-intestinal (GI) cancers
Chronic Liver Disease (CLD) controls with no current or history of cancer
CLD controls are USA and non USA residents
CLD controls are frequency matched to CGC cases by age (5 years), gender, and race
CLD controls are patients are diagnosed with or without liver biopsy (core or fine needle aspiration)
CLD controls must not have evidence liver cancer diagnosis by computed tomography (CT) or magnetic resonance imaging (MRI)

Exclusion

None

What this trial measures

  • Significant factors that may contribute to the etiology of biliary tree cancerthrough study completion, an average of 1 year