Study for Alcohol and Nicotine Use Disorder
This study is for adults who want to reduce their alcohol use and stop smoking. It's testing a behavioral treatment called Contingency Management (CM), which offers incentives for submitting urine samples that show no alcohol. Some participants will receive incentives for simply submitting samples, regardless of the result. This treatment is combined with varenicline (a medication for smoking cessation) and counseling videos. The study aims to see how well CM can help people decrease their alcohol and tobacco use over a 12-week treatment period and then for 7 months afterward. To join, you must be 18 or older, seeking treatment for both alcohol use disorder (AUD) and smoking, and meet specific criteria for alcohol consumption. The current recruitment status is unclear.
- Study design
- This is a randomized controlled trial, meaning participants are assigned by chance to different treatment groups. The study plans to enroll 205 participants.
- What's involved
- Participants will submit urine samples. The study involves a 12-week treatment period and a 7-month follow-up period.
- Compensation
- Not stated in the trial record.
- Follow-up
- Participants will be followed for 7 months after the 12-week treatment period.
AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.
Pharmaceutically-Enhanced Reinforcement for Reduced Alcohol and Smoking
At a glance
Conditions
Where it's being run
1 sites across 1 statesStudy leadership
- Sterling M McPherson, PhD · PRINCIPAL_INVESTIGATOR · Washington State University
Who to contact
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What this trial measures
- Change in Biochemically Verified Alcohol Use12-week treatment period and 7-month follow-up period
Consumption of alcohol between participants randomized to CM+TAU vs NC+TAU assessed by alcohol EtG values (collected 3x weekly from weeks 1-14, and once at weeks 18, 30, 42).
- Change in Biochemically Verified Tobacco Use12-week treatment period and 7-month follow-up period
Consumption of tobacco between participants randomized to CM+TAU vs NC+TAU assessed by tobacco CO and COT values (collected 3x weekly from weeks 1-14, and once at weeks 18, 30, 42).