Imaging Study for Head and Neck Cancer

This study is looking at new ways to image head and neck squamous cell carcinoma (a type of cancer). It compares a special imaging scan using [89Zr]Panitumumab-PET/MRI with the standard imaging scan, (18F-FDG)-PET/MRI. The goal is to see if the new scan can more accurately show the size and location of tumors before surgery. You could join if you have newly diagnosed head and neck squamous cell carcinoma, are scheduled for surgery, and your cancer has not spread to lymph nodes. This study is for imaging only and will not change your treatment plan. Researchers will measure the quality of the images taken 5-9 days before your surgery. The study is currently unclear on its recruitment status and plans to enroll 14 participants.

Study design
This is a single-center, non-randomized pilot study. It is open-label, meaning both you and the study team will know which imaging agent you receive. It plans to include 14 participants.
What's involved
You will have [89Zr]Panitumumab-PET/MRI imaging. You will also have a phone call to discuss the study and complete an MRI screening form before your first visit.
Compensation
Not stated in the trial record.
Follow-up
Image quality will be measured 5-9 days prior to surgery.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT05183048

Comparison of 89Zr Panitumumab and (18)F-Fluorodeoxyglucose to Identify Head and Neck Squamous Cell Carcinoma

Recruiting
EARLY_PHASE1Ages 18+InterventionalDiagnostic
University of Alabama at Birmingham
~14 participants
Updated 2025-12-26 on ClinicalTrials.gov
What's tested:[89Zr]Panitumumab Tracer

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Image Quality
Measured over 5-9 days prior to surgery
Head and Neck Squamous Cell Carcinoma
1 sites across 1 states
Alabama1
  • Suzanne Lapi, PhD · PRINCIPAL_INVESTIGATOR · University of Alabama at Birmingham

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  • Image Quality5-9 days prior to surgery

    Diagnostic image quality of \[89Zr\]Panitumumab PET imaging in patients with newly diagnosed HNSCC. Standardized Uptake Values (SUVs) will be measured.