Observational Study of Treatments for Benign Thyroid Nodules
This study is looking at two ways to treat benign (non-cancerous) thyroid nodules: surgery (Thyroidectomy) or a procedure called Radiofrequency Ablation (RFA). RFA uses heat to shrink the nodules. Researchers want to see how well these treatments work and how they affect your quality of life. They will compare changes in the size of your nodules and your thyroid hormone levels at 6 and 12 months after treatment. They will also ask you to complete a survey about your quality of life after 12 months. You can join if you are an adult (18 or older) with benign thyroid nodules. You cannot join if you have certain heart problems or are pregnant.
- Study design
- This is an observational study, meaning researchers will collect information about your treatment and outcomes. It aims to include 100 participants.
- What's involved
- This is a data collection study where you would give access to information generated before and after your treatment. The study measures outcomes at 6 and 12 months.
- Compensation
- Not stated in the trial record.
- Follow-up
- Participants will be followed for 12 months after treatment, with measurements taken at 6 and 12 months.
AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.
RFA of Benign Thyroid Nodules: Clinical Outcomes and Quality of Life Study
At a glance
Conditions
NCT05189314
Where you'd take part
This study runs at 1 site. They're the same protocol — you choose where, and that choice sets who your contact draft is addressed to.
Columbia University
New York, New Yorkstudy coordinator listed
Recruiting
Sites open and close at different times, so the status above is per site — it can differ from the study's overall status.
Study leadership
- Jennifer H Kuo, MD MS · PRINCIPAL_INVESTIGATOR · Columbia University
Who to contact
Opens a ready-to-send draft in your own email app — review before sending.
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Inclusion
Exclusion
What this trial measures
- Percent Volume Change of Nodules6 months and 12 months
Percent Volume Change of Nodules: ((Volume (baseline) - Volume (\*m\*))/Volume(baseline))\*100
- Change in Thyroid Stimulating Hormone (TSH)6 months and 12 months
Change in serum TSH
- ThyPRO 39 Survey Score12 months
The Thypro 39 is a survey assessing quality of life in patients with thyroid disease. Scores range from 0-100 with a higher score indicating a worse outcome.