This study is for young people (ages 10-30) who have had a hematopoietic cell transplant (HCT) for certain blood cancers or conditions like leukemia or aplastic anemia, between 6 months and 4 years ago. It's looking at whether a dietary supplement called Nicotinamide Riboside (NR) and a home-based exercise program can improve muscle strength. Researchers want to see if these interventions can help with muscle loss (sarcopenia) that can happen after HCT. The main goal is to measure changes in leg muscle strength after 16 weeks. The study is currently recruiting 80 participants, but its status is unclear.

Study design

This is a randomized, placebo-controlled study with 80 planned participants. It will compare the effects of Nicotinamide Riboside and an exercise program.

What's involved

Participants will take either Nicotinamide Riboside or a placebo and follow a home-based exercise program for 16 weeks. Muscle strength will be measured at the beginning and after 16 weeks.

Compensation

Not stated in the trial record.

Follow-up

The primary outcomes are measured from baseline to 16 weeks.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.