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Understanding Your Body's Microbes: A Comprehensive Registry

This study is creating a detailed registry of the bacteria and fungi (microbes) that live on and inside healthy people. Researchers want to understand how these microbes differ across various body sites and how they relate to things like your diet, medical history, and where you live. You would be asked to complete a questionnaire and provide samples of your stool, skin, and oral rinse. The goal is to identify unique patterns of microbes and how they interact with each other. This is an observational study, meaning no treatments are given, and it aims to enroll 5000 healthy volunteers aged 18 and older. The study is currently recruiting, but its overall status is unclear.

Study design
This is an observational study planning to enroll 5000 healthy volunteers. It is not testing a specific drug or treatment.
What's involved
You would complete a questionnaire and provide stool, skin swab, and oral rinse samples. These procedures would occur over an average of 10 years.
Compensation
Not stated in the trial record.
Follow-up
Participants will be followed through study completion, which is an average of 10 years.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT05196061

Human Skin and Gut Mycobiome and Bacteriome Comprehensive Registry

Recruiting
Not specifiedAges 18+Observational
University Hospitals Cleveland Medical Center
~5,000 participants
Updated 2026-04-13 on ClinicalTrials.gov
What's tested:QuestionnaireStool sampleSkin swabOral rinse

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
whole-body and site-specific microbiome profiles
Measured over through study completion, an average of 10 year
+2 more outcomes measured

Conditions

Healthy Volunteers

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Healthy Volunteers

NCT05196061

Where you'd take part

This study runs at 1 site. They're the same protocol — you choose where, and that choice sets who your contact draft is addressed to.

  • University Hospitals Cleveland Medical Center

    Cleveland, Ohiono site contact published

    Recruiting

Sites open and close at different times, so the status above is per site — it can differ from the study's overall status.

Who to contact

Mahmoud Ghannoum, PhD
[email protected]
216-844-7834
Email the study team

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Eligibility criteria

Inclusion

Capable of giving informed consent.
Able and willing to complete all required specified study procedures

Exclusion

Antibiotic or antifungal use whether topical or systemic in the past 2 or 4 weeks, respectively.
Unable and/or unwilling to complete all required study procedures.

What this trial measures

  • whole-body and site-specific microbiome profilesthrough study completion, an average of 10 year

    Identify and characterize whole-body and site-specific microbiome profiles.

  • Phenotypic microbiome profiles unique to individual parametersthrough study completion, an average of 10 year

    Identify phenotypic microbiome profiles unique to individual parameters such as demographics, medical diagnoses, diet; etc.

  • bacterial-bacterial, fungal-fungal and bacterial-fungal correlation analysisthrough study completion, an average of 10 year

    Perform bacterial-bacterial, fungal-fungal and bacterial-fungal correlation analysis to identify potential synergistic and antagonistic species within these unique profiles.