Novel Coding Strategies for Children With Cochlear Implants
This study aims to improve how cochlear implants help people hear by testing different ways to process sound. Researchers will compare how people with and without cochlear implants hear sounds. They will look at how different sound coding strategies, like Single-Electrode Pulse Train, Modulation Detection Threshold (MDT) and Gap Detection Tasks, and Electric-only spectral resolution, affect hearing. The study is open to individuals aged 6 to 80 years old who have cochlear implants (implanted before age 2 or post-lingually) or normal hearing. The main goals are to see if these new strategies improve how well people hear loudness, and how well they can distinguish sounds over time and across different pitches. The study is currently unclear on its recruitment status and plans to enroll 190 participants.
- Study design
- This is an interventional study that plans to enroll 190 participants. It will compare information from individuals with and without cochlear implants.
- What's involved
- Participants will have their loudness growth, temporal resolution (how well they hear sounds over time), and spectral resolution (how well they distinguish different pitches) measured at a baseline visit and again at week 10.
- Compensation
- Not stated in the trial record.
- Follow-up
- Participants will be followed for changes in loudness growth, temporal resolution, and spectral resolution up to week 10.
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Novel Coding Strategies for Children With Cochlear Implants
At a glance
Conditions
Where it's being run
1 sites across 1 statesStudy leadership
- David M Landsberger, MD · PRINCIPAL_INVESTIGATOR · NYU Langone Health
Who to contact
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Do you actually qualify for this trial?
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Inclusion
Exclusion
What this trial measures
- Change in loudness growth in Cochlear Implant participantsBaseline Visit (Day 1) , Visit week 10
Power functions will be fit for each of the loudness growth curves. Data will be analyzed using a mixed-design ANOVA with the two groups as the between-subjects factor and electrode and rate as within-subject factors.
- Change in temporal resolution in Cochlear implant participantsBaseline Visit (Day 1) , Visit week 10
A mixed-effect ANOVA will be conducted to determine if there is an effect of age group (children vs adults) and hearing condition (CI vs NH) for both modulation detection and gap detection tasks. Post-hoc two-sample t-tests will compare differences between NH and CI children as well as NH and CI adults. Post-hoc paired t-tests will compare differences between adults and children for both the NH and the CI populations.
- Change in spectral resolution in Cochlear implant participantsBaseline Visit (Day 1) , Visit week 10
A one-way ANOVA will be used to calculate the differences between the four groups. If significant, post-hoc t-tests will be performed using Rom's modified Bonferroni Type I error correction.
- Difference in performance between the reduced channel map and the full mapBaseline Visit (Day 1) , Visit week 10
A mixed-design ANOVA will be conducted for each of the tests with subject population as the between-subjects factor and sound coding strategy as the within-subjects factor