myAirvo 3 for COPD Patients in the Home

This study is looking at whether using a device called myAirvo 3, which provides high-flow warmed and humidified air through your nose (High Flow Nasal Therapy or HFNT), can help people with moderate to very severe Chronic Obstructive Pulmonary Disease (COPD) stay healthier at home. You might be able to join if you are 30 years or older, have moderate to very severe COPD, and have recently been hospitalized for a severe COPD flare-up. The main goal is to see if using myAirvo 3 increases the time until your first moderate or severe COPD flare-up, or death, over one year. The study also looks at how myAirvo 3 affects hospitalizations, quality of life, and breathing.

Study design
This is a randomized controlled study with 642 participants, comparing myAirvo 3 plus usual COPD care to usual COPD care alone.
What's involved
If you participate, you will use the myAirvo 3 device if assigned to that group, and use a pulse oximeter daily to measure your heart rate and oxygen levels, entering the data on a smartphone.
Compensation
Not stated in the trial record.
Follow-up
Participants will be followed for at least one year, and up to two years, to track outcomes like exacerbations and mortality.

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NCT05204888

myAirvo 3 (High Flow Nasal Therapy; HFNT) for COPD Patients in the Home

Recruiting
NAAges 30+InterventionalTreatment
Temple University
~642 participants
Updated 2025-02-06 on ClinicalTrials.gov
What's tested:myAirvo3Pulse oximeter

At a glance

Recruiting sites
27 of 27 listed sites are recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
To determine if myAirvo 3 use increases the time to first moderate exacerbation/severe exacerbation (hospitalization)/all-cause mortality in patients with moderate to very severe COPD.
Measured over 1 year
COPD
27 sites across 16 states
Florida5
Pennsylvania5
Ohio3
Massachusetts2
Alabama1
Arizona1
Illinois1
Iowa1

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Eligibility criteria

Exclusion

subjects with a STOPBang questionnaire score of \> 5 may be eligible if a recent sleep study (within the previous 3 months) shows the absence of obstructive sleep apnea or the subject has, or is at risk of OSA, but refuses to use an OSA device and all other eligibility criteria are met.
  • To determine if myAirvo 3 use increases the time to first moderate exacerbation/severe exacerbation (hospitalization)/all-cause mortality in patients with moderate to very severe COPD.1 year

    Time to first moderate or severe COPD exacerbation