Valbenazine for Trichotillomania (Hair-Pulling Disorder)
This study is testing valbenazine, an oral capsule, to see if it can help adults with trichotillomania (hair-pulling disorder). Participants will receive either valbenazine or a placebo (an inactive capsule that looks the same) for 12 weeks. After this, all participants will receive valbenazine for another 12 weeks. The study aims to find the best dose of valbenazine (either 40mg or 80mg) and measure how much hair-pulling symptoms improve using a special scale. You can join if you are an adult between 18 and 65 years old, in good health, and on a stable psychiatric medication regimen. The current recruitment status is unclear.
- Study design
- This is a double-blind, placebo-controlled study where participants are randomly assigned to receive either valbenazine or placebo. Approximately 20 participants will be enrolled.
- What's involved
- You would take an oral capsule daily for 24 weeks, with the first 12 weeks being either valbenazine or placebo, and the next 12 weeks being valbenazine. Your dose may be adjusted during the first few weeks.
- Compensation
- Not stated in the trial record.
- Follow-up
- You will have follow-up assessments at the end of week 26, which is two weeks after your last dose of valbenazine.
AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.
Efficacy of Valbenazine for the Treatment of Trichotillomania in Adults
At a glance
Conditions
Where it's being run
1 sites across 1 statesStudy leadership
- Michael H. Bloch, MD · PRINCIPAL_INVESTIGATOR · Yale University
Who to contact
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What this trial measures
- Change in Massachusetts General Hospital Hairpulling Scale (MGH-HPS) from baseline to Week 12baseline to week12
Massachusetts General Hospital Hairpulling Scale (MGH-HPS) scores range from 0-28 with 28 being the most severe. The lower the total score, the lower the severity level. This scale is given and measured once every 2 weeks for a total of 12 weeks.