Scalp Cooling for Hair Loss in Patients of Color Receiving Chemotherapy

This study is looking at different ways to use scalp cooling to prevent hair loss (alopecia) caused by chemotherapy. Researchers want to see if specific hairstyling techniques, like braids/cornrows/twists or using conditioner and water emulsion, can make scalp cooling more effective for people of color. They also want to understand how scalp cooling works at a molecular level and identify markers that predict success. You may be able to join if you are female, 18 or older, have curly or kinky hair (type 3 or 4), and are starting at least 4 cycles of taxane-based chemotherapy for breast, non-small cell lung, or gynecologic cancer. The study will measure how severe hair loss is and any side effects up to about 6 months after chemotherapy ends. This study aims to address the limited representation of minority groups in previous scalp cooling research.

Study design
This is an interventional study, meaning you will receive a specific treatment. It plans to enroll 41 participants.
What's involved
Not specified in the trial record.
Compensation
Not stated in the trial record.
Follow-up
Your hair loss and any side effects will be monitored for about 6 months after your chemotherapy is completed.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT05213936

Scalp Cooling for Chemotherapy-Induced Alopecia in Patients of Color

Recruiting
NAAges 18+InterventionalTreatment
Montefiore Medical Center
~41 participants
Updated 2026-07-16 on ClinicalTrials.gov
What's tested:Scalp cooling with hairstyleScalp cooling with conditioner and water emulsion

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Severity of chemotherapy-induced alopecia - hair count density
Measured over 4 weeks after completion of chemotherapy, up to ~6 months total
+1 more outcome measured
Alopecia
1 sites across 1 states
New York1
  • Beth McLellan, MD · PRINCIPAL_INVESTIGATOR · Montefiore Medical Center

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  • Severity of chemotherapy-induced alopecia - hair count density4 weeks after completion of chemotherapy, up to ~6 months total

    Severity of chemotherapy-induced alopecia, or CIA, as determined by hair count density from trichoscopy will be assessed. Hair count density (hair counts/cm\^2) will be summarized by study arm and analyzed using a T-test.

  • Severity of chemotherapy-induced alopecia - adverse events4 weeks after the completion of chemotherapy, up to ~6 months total

    Severity of CIA will also be evaluated based on Common Terminology Criteria for Adverse Events (CTCAE Version 5.0) grading. Results will be summarized by study arm and analyzed Fisher's exact test.