Scalp Cooling for Hair Loss in Patients of Color Receiving Chemotherapy
This study is looking at different ways to use scalp cooling to prevent hair loss (alopecia) caused by chemotherapy. Researchers want to see if specific hairstyling techniques, like braids/cornrows/twists or using conditioner and water emulsion, can make scalp cooling more effective for people of color. They also want to understand how scalp cooling works at a molecular level and identify markers that predict success. You may be able to join if you are female, 18 or older, have curly or kinky hair (type 3 or 4), and are starting at least 4 cycles of taxane-based chemotherapy for breast, non-small cell lung, or gynecologic cancer. The study will measure how severe hair loss is and any side effects up to about 6 months after chemotherapy ends. This study aims to address the limited representation of minority groups in previous scalp cooling research.
- Study design
- This is an interventional study, meaning you will receive a specific treatment. It plans to enroll 41 participants.
- What's involved
- Not specified in the trial record.
- Compensation
- Not stated in the trial record.
- Follow-up
- Your hair loss and any side effects will be monitored for about 6 months after your chemotherapy is completed.
AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.
Scalp Cooling for Chemotherapy-Induced Alopecia in Patients of Color
At a glance
Conditions
Where it's being run
1 sites across 1 statesStudy leadership
- Beth McLellan, MD · PRINCIPAL_INVESTIGATOR · Montefiore Medical Center
Who to contact
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What this trial measures
- Severity of chemotherapy-induced alopecia - hair count density4 weeks after completion of chemotherapy, up to ~6 months total
Severity of chemotherapy-induced alopecia, or CIA, as determined by hair count density from trichoscopy will be assessed. Hair count density (hair counts/cm\^2) will be summarized by study arm and analyzed using a T-test.
- Severity of chemotherapy-induced alopecia - adverse events4 weeks after the completion of chemotherapy, up to ~6 months total
Severity of CIA will also be evaluated based on Common Terminology Criteria for Adverse Events (CTCAE Version 5.0) grading. Results will be summarized by study arm and analyzed Fisher's exact test.