This study is looking at different ways to screen for anal cancer in women who have had certain HPV-related conditions (like cervical, vulvar, or vaginal pre-cancers or early cancers). Researchers want to see how well tests like anal cytology (a 'Pap test' for the anus) and HPV testing work to find early signs of anal cancer. They will also perform a digital rectal exam. You might be able to join if you are a woman aged 35 or older, have a history of high-grade HPV-related disease in your lower genital tract, and do not have HIV. The main goal is to find out how accurate these screening methods are. The study is currently unclear on its status and plans to enroll 300 participants.

Study design

This is a single-arm study, meaning all 300 participants will receive the same diagnostic tests. It is an interventional study, focusing on diagnostic tests for anal cancer screening.

What's involved

You would have an initial visit for diagnostic tests, including anal cytology, self-collected and clinician-collected HPV specimens, and a digital rectal exam. You would then have follow-up evaluations at 12 and 24 months.

Compensation

Not stated in the trial record.

Follow-up

Participants will be followed for 24 months after their initial evaluation.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.