This study is looking at whether a neuromodulation device can help people with systolic heart failure (when your heart muscle can't pump blood as well as it should). Researchers want to see if stimulating a nerve in the ear, called the vagus nerve, can improve how far you can walk in 6 minutes. You might receive either the active neuromodulation device, which attaches to the tragus of your ear, or a sham device, which attaches to your earlobe. Both devices are used for 1 hour daily for 12 weeks. This study is open to people aged 18 to 85 with systolic heart failure whose heart's pumping ability (ejection fraction) is 50% or less. The study aims to enroll 158 participants.

Study design

This is a randomized, double-blind study comparing active neuromodulation to a sham treatment. It plans to include 158 participants.

What's involved

Participants will use a neuromodulation device for 1 hour daily for 12 weeks. You will have a 6-minute walk test and complete a heart failure questionnaire at the beginning and after 3 months.

Compensation

Not stated in the trial record.

Follow-up

Participants will be assessed at 3 months after starting treatment.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.