Tempus CRC Surveillance Study for Colorectal Cancer

This observational study is looking at people with colorectal cancer (CRC) to understand how a blood test called ctDNA biomarker profiling can help monitor their disease. You might be able to join if you have known or suspected colorectal cancer (stages I to IVA) and are planning to have or have already had surgery to remove the cancer. The study will follow participants to see how long they live without their cancer coming back (recurrence-free survival) over two years. The current recruitment status is unclear.

Study design
This is an observational study involving 300 participants. It is not a treatment study, but rather observes participants alongside their standard care.
What's involved
You would need to provide additional blood samples during your routine follow-up visits after surgery.
Compensation
Not stated in the trial record.
Follow-up
Participants will be followed for two years to measure recurrence-free survival.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT05234177

Tempus CRC Surveillance Study: A ctDNA Biomarker Profiling Study of Patients With CRC Using NGS Assays

Recruiting
Not specifiedAges 18+Observational
Tempus AI
~300 participants
Updated 2025-05-06 on ClinicalTrials.gov
What's tested:Observation

At a glance

Recruiting sites
20 of 20 listed sites are recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Recurrence-Free Survival
Measured over 2 years
Colorectal Cancer
20 sites across 12 states
Missouri5
Ohio5
Arkansas1
California1
Maryland1
Nebraska1
North Carolina1
Oklahoma1
  • Kristiyana Kaneva, MD, MS · PRINCIPAL_INVESTIGATOR · Tempus AI, Inc.

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Do you actually qualify for this trial?

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Eligibility criteria

Inclusion

Known or suspected colorectal adenocarcinoma (Stage I to IVA disease)
Planning to undergo or has undergone a surgical resection for suspected adenocarcinoma of the colon or rectum with curative intent.
18 years old or older
Willing and able to provide informed consent
Willing to have additional blood samples collected during routine surveillance visits

Exclusion

Not willing to have additional blood samples collected
Pathology that is not consistent with colorectal adenocarcinoma
  • Recurrence-Free Survival2 years

    Recurrence-Free Survival as assessed by standard radiographic imaging, measured from the day of completion of definitive treatment to first radiographic recurrence or death