Secretin in Refeeding for Anorexia in Adolescence

This observational study is looking at how the hormone secretin might be involved in anorexia nervosa, specifically in teenagers and young adults aged 13 to 24. Researchers want to see if secretin levels are different in patients with anorexia who urinate a lot compared to those who urinate normal amounts. This is important because excessive urination and changes in how the body handles acid and base can make hospital stays longer for these patients. To participate, you would have one extra blood draw before and after a meal, and one extra urine sample after the meal, all while you are already in the hospital for nutritional support. The study is currently unclear on its status and plans to enroll 10 participants.

Study design
This is an observational study planning to enroll 10 participants. It is not specified if it is a specific phase of research.
What's involved
You would have one extra blood draw before and after one meal during your hospitalization. You would also provide one extra urine sample after the meal.
Compensation
Not stated in the trial record.
Follow-up
The primary measurement for this study is taken at 1 hour after a meal.

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NCT05235867

Secretin in Refeeding

Recruiting
Not specifiedAges 13–24Observational
University of California, Los Angeles
~10 participants
Updated 2026-02-12 on ClinicalTrials.gov

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Change in secretin
Measured over 1 hour
Anorexia in Adolescence
1 sites across 1 states
California1

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Eligibility criteria

Inclusion

Group 1:
male and female patients
age 13-24 years
diagnosis of restrictive-type anorexia nervosa
hospitalization for nutritional support
\>4 cc/kg/day of urine output (a.k.a. "fluid dumpers"; n=5)
Group 2:
male and female patients
age 13-24 years
diagnosis of restrictive-type anorexia nervosa
hospitalization for nutritional support
\<2 cc/kg/d of urine output (a.k.a. "non-dumpers"; n=5)

Exclusion

5150 hold
Anti-depressant, anti-psychotic, or anticonvulsant medications
Previous hospitalization within the past 6 months
Underlying metabolic disorder not related to anorexia nervosa (including chronic kidney disease, renal tubular disorders, and underlying endocrine disorders)
Pregnancy
NG or G-tube feeds after day 2 of hospitalization
\> 10% of nutritional needs from supplemental feeds
  • Change in secretin1 hour

    Change in secretin value from pre- to post- meal