This study is for individuals with repaired Tetralogy of Fallot (rTOF), a heart condition, who are scheduled to receive a transcatheter pulmonary valve replacement (TPVR). People with rTOF can be at risk for a fast heart rhythm called ventricular tachycardia (VT) and sudden cardiac death. Researchers want to understand if TPVR can help reduce this risk. They will use a diagnostic test called electroanatomic substrate mapping with an HD Grid catheter and Ensite X system to create a detailed map of the heart's right ventricle before the TPVR procedure. This will help them identify areas that might cause VT and see how the new valve interacts with these areas. The study aims to enroll 60 participants who weigh at least 25 kg.

Study design

This is an interventional study with a planned enrollment of 60 participants. It is not specified if it is randomized or blinded.

What's involved

If you participate, you will undergo a diagnostic electrophysiology mapping procedure to create a 3-dimensional map of your heart's right ventricle before your TPVR. This mapping uses a high-density multielectrode catheter and an electroanatomic mapping system.

Compensation

Not stated in the trial record.

Follow-up

Researchers will track future arrhythmic events for up to 10 years after the procedure.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.