High Fiber Diet and Exercise for Heart Failure with Preserved Ejection Fraction (HFpEF)

This study is looking at how a high-fiber diet, high-intensity interval exercise, or a combination of both can improve health for people with Heart Failure with Preserved Ejection Fraction (HFpEF). HFpEF is a type of heart failure where your heart can pump blood normally, but it's too stiff to fill properly. You might be able to join if you are at least 40 years old, have HFpEF with NYHA class II-III symptoms (meaning you have some limitations with physical activity), have doctor's approval for exercise and diet, and are fully vaccinated for COVID-19. The study will measure success by looking at your VO2peak (a measure of how well your body uses oxygen during exercise) after 4 weeks. The current recruitment status is unclear.

Study design
This interventional study plans to enroll 36 participants. It is not specified if it is randomized, blinded, or what phase it is in.
What's involved
If you join, you would participate in either three supervised stationary cycling exercise sessions per week for 4 weeks, follow a personalized 7-day DASH diet meal plan, or do both.
Compensation
Not stated in the trial record.
Follow-up
The primary outcome is measured at 4 weeks, indicating the study duration for this measurement.

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NCT05236413

The Effect of a High Fiber Diet and High-Intensity Interval Exercise in Patients With HFpEF

UNKNOWN
NAAges 40+InterventionalSupportive care
University of Virginia
~36 participants
Updated 2024-05-07 on ClinicalTrials.gov
What's tested:High Intensity Interval ExerciseDietary Approaches to Stop Hypertension (DASH) DietExercise + DASH Diet

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
VO2peak
Measured over 4 weeks
Heart Failure With Preserved Ejection Fraction
1 sites across 1 states
Virginia1
  • Siddhartha S Angadi, PhD · PRINCIPAL_INVESTIGATOR · University of Virginia

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Do you actually qualify for this trial?

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Eligibility criteria

Inclusion

≥40 years of age
Diagnosed with heart failure with preserved ejection fraction
NYHA class II-III symptoms
Physician clearance to undergo exercise training
Physician clearance to consume DASH diet
Complete COVID-19 vaccination status

Exclusion

Unstable angina
Myocardial infarction in the past 4 weeks
Uncompensated heart failure
NYHA class IV symptoms
Complex ventricular arrhythmias
Musculoskeletal contraindications to stationary bicycling exercise
Symptomatic severe aortic stenosis
Acute pulmonary embolus
Acute myocarditis
Uncontrolled hypertension
Medication non-compliance
Unable to follow DASH diet
Food allergies (Nuts, wheat)
Pregnant women
  • VO2peak4 weeks

    Change in VO2peak (L/min) measured pre- and post-intervention